Multiple studies have reported a male bias in incidence and/or prevalence of malaria
infection in males compared to females. To test the hypothesis that sex-based differences in …

Background Natural immunity to Plasmodium falciparum has been widely studied, but its
effects on parasite dynamics are poorly understood. Acquisition and clearance rates of …

Background Individuals living in areas of high malaria transmission often have different
Plasmodium falciparum clones detected in the peripheral blood over time. The aim of this …

Genotyping Plasmodium falciparum parasites in longitudinal studies provides a robust
approach to estimating force of infection (FOI) in the presence of superinfections. The …

The effect of acquired immunity on the duration of Plasmodium falciparum infections is
unclear, although this is an important term in models of malaria transmission. It is …

Prolonged carriage of Plasmodium falciparum, in humans during the dry season is critical for
parasite survival, as the infected subjects constitute a major reservoir in the absence of …

Background: The first models of malaria transmission assumed a completely mixed and
homogeneous population of parasites. Recent models include spatial heterogeneity and …

Few data exist on the incidence or duration of natural Plasmodium falciparum infections in
high-transmission settings. School-aged children (SAC) carry a disproportionate burden of …

Background: Monitoring malaria transmission is a critical component of efforts to achieve
targets for elimination and eradication. Two commonly monitored metrics of transmission …

Background and Objectives Experimental models show a male bias in murine malaria;
however, extant literature on biases in human clinical malaria is inconclusive. Studies in …