Extensive studies demonstrate the importance of the STING1 (also known as STING) protein
as a signaling hub that coordinates immune and autophagic responses to ectopic DNA in …

Alterations in the cGAS-STING DNA-sensing pathway affect intestinal homeostasis. We
sought to delineate the functional role of STING in intestinal inflammation. Increased STING …

The stimulator of interferon genes (STING) connects microbial cytosolic sensing with host
cell effector functions. STING signaling plays a central role in cyclic dinucleotides (CDNs) …

STING (stimulator of interferon genes) is a cytosolic sensor for cyclic dinucleotides and also
an adaptor molecule for intracellular DNA receptors. Although STING has important …

Stimulator of IFN genes (STING) is a cytoplasmic innate immune sensor for cyclic
dinucleotides that also serves a dual role as an adaptor molecule for a number of …

The gastrointestinal tract is a highly complex microenvironment under constant interaction
with potentially harmful pathogens. Inflammatory bowel disease (IBD) is an archetypical …

Stimulator of interferon response cGAMP interactor 1 (STING1), also known as TMEM173, is
an immune adaptor protein that governs signal crosstalk that is implicated in many …

Innate immunity is regulated by a broad set of evolutionary conserved receptors to finely
probe the local environment and maintain host integrity. Besides pathogen recognition …

Abstract Background & Aims T helper 1 (Th1) effector cells are implicated in inflammatory
bowel disease. The stimulator of interferon genes (STING), an intracellular DNA sensor, has …

Stimulator of interferon genes (STING) has been shown to play a critical role in orchestrating
immune responses to various pathogens through sensing cyclic dinucleotides. However …