Assessment of Lab4P probiotic effects on cognition in 3xTg-AD Alzheimer's disease model mice and the SH-SY5Y neuronal cell line

TS Webberley, RJ Bevan, J Kerry-Smith, J Dally… - International Journal of …, 2023 - mdpi.com
Aging and metabolic syndrome are associated with neurodegenerative pathologies
including Alzheimer's disease (AD) and there is growing interest in the prophylactic potential …

The impact of probiotic supplementation on cognitive, pathological and metabolic markers in a transgenic mouse model of Alzheimer's disease

TS Webberley, G Masetti, RJ Bevan… - Frontiers in …, 2022 - frontiersin.org
Brain degenerative disorders such as Alzheimer's disease (AD) can be exacerbated by
aberrant metabolism. Supplementation with probiotic bacteria is emerging as a promising …

Multi-strain probiotics ameliorate Alzheimer's-like cognitive impairment and pathological changes through the AKT/GSK-3β pathway in senescence-accelerated …

Q Xiao-Hang, C Si-Yue, T Hui-Dong - Brain, Behavior, and Immunity, 2024 - Elsevier
Background Alzheimer's disease (AD), the most prevalent type of dementia, still lacks
disease-modifying treatment strategies. Recent evidence indicates that maintaining gut …

Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels

L Bonfili, V Cecarini, S Berardi, S Scarpona… - Scientific reports, 2017 - nature.com
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …

[HTML][HTML] Probiotics improve cognitive impairment by decreasing Bacteria-related pattern recognition receptor-mediated inflammation in the gut-brain Axis of mice

XQ Yang, Y Zhao, L Xue, HS Wang, J Zeng… - Journal of Integrative …, 2023 - imrpress.com
Introduction: Some studies have found that probiotics can improve cognitive impairment in
Alzheimer's disease, although the specific molecular mechanism by which this occurs has …

Slowing Alzheimer's disease progression through probiotic supplementation

D Medeiros, K McMurry, M Pfeiffer… - Frontiers in …, 2024 - frontiersin.org
The lack of affordable and effective therapeutics against cognitive impairment has promoted
research toward alternative approaches to the treatment of neurodegeneration. In recent …

Ameliorative effects of probiotics in AlCl3-induced mouse model of Alzheimer's disease

M Hamid, S Zahid - Applied Microbiology and Biotechnology, 2023 - Springer
In recent years, gut microbiome alterations have been linked with complex underlying
mechanisms of neurodegenerative disorders including Alzheimer's disease (AD). The gut …

Probiotics as potential therapeutic options for Alzheimer's disease

HF Ji, L Shen - Applied Microbiology and Biotechnology, 2021 - Springer
The steadily increasing prevalence of Alzheimer's disease (AD) worldwide and the lack of
effective therapeutic agent attract novel therapeutic approach in recent years. In view of the …

Therapeutic implications of probiotics in the gut microbe-modulated neuroinflammation and progression of Alzheimer's disease

T Murai, S Matsuda - Life, 2023 - mdpi.com
Alzheimer's disease (AD) is characterized by the accumulation of specific proteins in the
brain. A recent study revealed that manipulating gut microbiota (GM) significantly reduced …

Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-amyloid aggregation in a preclinical Alzheimer's disease model

PC Bello-Medina, K Corona-Cervantes… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a multifactorial pathology characterized by β-amyloid (Aβ)
deposits, Tau hyperphosphorylation, neuroinflammatory response, and cognitive deficit …