Abstract α-Amyrin is a plant-originated high-valued triterpene that is highly effective against
several pathological ailments. α-Amyrin production by engineered Saccharomyces …

α-Amyrin is a plant-derived pentacyclic triterpenoid, with a lot of important physiological and
pharmacological activities. The formation of α-amyrin from (3 S)-2, 3-oxidosqualene is …

Triterpenoids are a highly diverse group of natural products and used particularly as
medicine. Here, a strategy combining stepwise metabolic engineering and transcriptional …

β-Amyrin is a plant-derived triterpenoid skeleton with wide applications in food and medical
industry. β-Amyrin biosynthesis in Saccharomyces cerevisiae is derived from the …

The study aims to enhance β-amyrin production in Saccharomyces cerevisiae by
peroxisome compartmentalization. First, overaccumulated squalene was determined as a …

The production of β-amyrin in Saccharomyces cerevisiae is still low due to the inability of
effectively regulating the endogenous metabolic pathway for competitive synthesis of β …

Background Amyrin is an important triterpenoid and precursor to a wide range of cosmetic,
pharmaceutical and nutraceutical products. In this study, we metabolically engineered the …

Using a degenerate primer designed from triterpene synthase sequences, we have isolated
a new gene from the medicinal plant Artemisia annua. The predicted protein is highly similar …

Alpha-amylases are important industrial enzymes with a wide range of applications.
Although medium-temperature alpha amylase (AmyE) has some practical advantages, its …

Glycyrrhetinic acid (GA) and its precursor, 11-oxo-β-amyrin, are typical triterpenoids found in
the roots of licorice, a traditional Chinese medicinal herb that exhibits diverse functions and …