Endometriosis: update of pathophysiology,(epi) genetic and environmental involvement

N Monnin, AJ Fattet, I Koscinski - Biomedicines, 2023 - mdpi.com
Endometriosis is a chronic disease caused by ectopic endometrial tissue. Endometriotic
implants induce inflammation, leading to chronic pain and impaired fertility. Characterized …

Recent insights explaining susceptibility to endometriosis—From genetics to environment

AS Pais, T Almeida‐Santos - WIREs Mechanisms of Disease, 2023 - Wiley Online Library
Endometriosis is a disease with a heterogeneous pathogenesis, explained by multiple
theories, and also with a polymorphic presentation. The purpose of this literature review is to …

[PDF][PDF] The link between environmental toxicant exposure and endometriosis

DL Anger, WG Foster - Front Biosci, 2008 - article.imrpress.com
Introduction 3. Epidemiological evidence 3.1. Phthalate esters 3.2. Polyhalogenated
aromatic hydrocarbons 3.2. 1. Polychlorinated biphenyls 3.2. 2. Dioxins and dioxin-like …

Endometriosis: a comprehensive update

S Gupta, A Harlev, A Agarwal - 2015 - Springer
Both animals and humans are exposed to toxins in the environment that may influence the
onset and progression of endometriosis. Human exposure occurs mainly through ingestion …

Endometriosis and environmental factors: A critical review

E Coiplet, B Courbiere, A Agostini, L Boubli… - Journal of Gynecology …, 2022 - Elsevier
This review provides an overview of current knowledge on the relationship between various
environmental factors and endometriosis. We successively searched for a given exposure …

Cellular and molecular basis for endometriosis-associated infertility

JAW Stilley, JA Birt, KL Sharpe-Timms - Cell and tissue research, 2012 - Springer
Endometriosis is a gynecological disease characterized by the presence of endometrial
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …

In utero exposure and endometriosis

G Benagiano, I Brosens - The Journal of Maternal-Fetal & Neonatal …, 2014 - Taylor & Francis
Adverse living and nutritional conditions in utero and in early infancy may influence the risk
of diseases in adult life, because fetal growth seems determined by interactions between the …

Epidemiology of endometriosis and its comorbidities

F Parazzini, G Esposito, L Tozzi, S Noli… - European Journal of …, 2017 - Elsevier
Genetic profile, inflammation, hormonal activity, menstrual cyclicity, organochlorine burden,
prostaglandin metabolism and immunological factors have been suggested to play a role in …

Role of inflammation and aromatase expression in the eutopic endometrium and its relationship with the development of endometriosis

H Maia Jr, C Haddad, G Coelho, J Casoy - Women's Health, 2012 - journals.sagepub.com
Epigenetic changes favoring the transcription of the aromatase gene in the endometrium
allow endometrial cells to survive in ectopic locations by producing estrogens that spare …

Future directions in endometriosis research

TM D'HOOGHE, C Kyama, S Debrock… - Annals of the New …, 2004 - Wiley Online Library
Endometriosis is an important gynecological disease, pathologically defined by the ectopic
presence of both endometrial glands and stroma, and clinically associated with pelvic pain …