Gray and white matter changes linking cerebral small vessel disease to gait disturbances

YJ Kim, HK Kwon, JM Lee, H Cho, HJ Kim, HK Park… - Neurology, 2016 - AAN Enterprises
Objective: To investigate the topographic changes of white matter (WM) integrity and cortical
thickness related to gait disturbances and determine whether these neural correlates …

Cortical thickness is associated with gait disturbances in cerebral small vessel disease

KF de Laat, AT Reid, DC Grim, AC Evans, R Kötter… - Neuroimage, 2012 - Elsevier
Although gait disturbances are present in a substantial portion of patients with cerebral small
vessel disease (SVD), their pathogenesis has not been clarified as they are not entirely …

Impact of regional white matter hyperintensities on specific gait function in Alzheimer's disease and mild cognitive impairment

N Ogama, H Endo, S Satake, S Niida… - Journal of cachexia …, 2021 - Wiley Online Library
Background Gait disturbance and musculoskeletal changes are evident in persons living
with Alzheimer's disease (AD). Because complex gait control requires the integration of …

Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease

KF De Laat, AM Tuladhar, AGW Van Norden, DG Norris… - Brain, 2011 - academic.oup.com
Gait disturbances are common in the elderly. Cerebral small vessel disease, including white
matter lesions and lacunars infarcts, is thought to disrupt white matter tracts that connect …

[HTML][HTML] Impact of small vessel disease in the brain on gait and balance

D Pinter, SJ Ritchie, F Doubal, T Gattringer, Z Morris… - Scientific reports, 2017 - nature.com
Gait and balance impairment is highly prevalent in older people. We aimed to assess
whether and how single markers of small vessel disease (SVD) or a combination thereof …

[HTML][HTML] White matter changes and gait decline in cerebral small vessel disease

HM van der Holst, AM Tuladhar, V Zerbi… - Neuroimage …, 2018 - Elsevier
The relation between progression of cerebral small vessel disease (SVD) and gait decline is
uncertain, and diffusion tensor imaging (DTI) studies on gait decline are lacking. We …

[HTML][HTML] Cognition mediates the relation between structural network efficiency and gait in small vessel disease

M Cai, MA Jacob, DG Norris, M Duering… - NeuroImage: Clinical, 2021 - Elsevier
Cerebral small vessel disease (SVD), including white matter hyperintensities (WMH),
microbleeds, lacunes, was related to gait disturbances, while the underlying mechanism is …

[HTML][HTML] Gait impairment and upper extremity disturbance are associated with total magnetic resonance imaging cerebral small vessel disease burden

Y Hou, Y Li, S Yang, W Qin, L Yang… - Frontiers in aging …, 2021 - frontiersin.org
Background and Purpose: Cerebral small vessel disease (cSVD)—including white matter
hyperintensities (WMHs), cerebral microbleeds (CMBs), lacunes, and enlarged perivascular …

Effect of small vessel disease burden and lacunes on gait/posture impairment in Parkinson's disease

H Chen, M Zhang, G Liu, X Wang, Z Wang, H Ma… - Neurological …, 2020 - Springer
Introduction The comorbidity of cerebral small vessel disease (CSVD) may worsen gait
impairment of Parkinson's disease (PD). However, the evidence remains scarce and …

Gait in elderly with cerebral small vessel disease

KF de Laat, AGW van Norden, RAR Gons… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Gait disorders are common in the elderly and are related to loss
of functional independence and death. White matter lesions (WMLs) may be related, but only …