Newborns, and especially those delivered preterm, are probably more prone to oxidative
stress than individuals later in life. Also during pregnancy, increased oxygen demand …

Oxidative stress contributes to the severity of several newborn conditions to the extent that
Saugstad coined the phrase “oxygen radical diseases of neonatology.” In order to …

Reactive oxygen species have a crucial role in the pathogenesis of perinatal diseases.
Exposure to inflammation, infections, or high oxygen concentrations is frequent in preterm …

Melatonin, an endogenously produced indoleamine, is a highly effective antioxidant, free
radical scavenger, and a primary circadian regulator. Melatonin has important antioxidant …

Reactive oxygen species (ROS) play a critical role in the pathogenesis of various diseases
during pregnancy and the perinatal period. Newborns are more prone to oxidative stress …

Introduction. Preterm infants are at risk of free radical‐mediated diseases from oxidative
stress (OS) injury. Increased free radical generation has been demonstrated in preterm …

Free radicals have been implicated in the pathogenesis of neonatal sepsis and its
complications. This study was conducted to determine the changes in the clinical status and …

Background: It is known that oxygen‐derived free radicals play an important role in the
pathogenesis of brain injury. Melatonin is a powerful scavenger of the oxygen free radicals …

Melatonin, an indoleamine derived from tryptophan and produced in the pineal gland and
other tissues [1, 2] is a potent antioxidant and inflammatory agent [1]. Specifically, the …

Oxidative stress is worldwide recognized as a fundamental component of the aging, a
process that begins before birth. There is a critical balance between free radical generation …