Background. Cancer‐associated fibroblasts (CAFs) can strongly modulate the response to
therapy of malignant tumor cells, facilitating their continuous proliferation and invading …

Fibroblast activation protein (FAP), overexpressed on cancer-associated fibroblasts (CAFs),
is a novel target for molecular imaging of various tumors. Recently, the development of …

Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

The tumor microenvironment (TME) surrounding tumor cells is a complex and highly
dynamic system that promotes tumorigenesis. Cancer-associated fibroblasts (CAFs) are key …

Metastatic malignancies have limited management strategies and variable treatment
responses. Cancer cells develop beside and depend on the complex tumor …

Simple Summary Fibroblast activation protein is a newly discovered biomarker in various
tumor types. Using inhibitors ligated with radiopharmaceuticals, nuclear medicine …

Simple Summary FAP-targeted radiotracers, recently introduced in cancer treatment,
accumulate in Cancer-Associated Fibroblasts (CAFs). CAFs are present in tumor lesions but …

Objective Fibroblast activation protein (FAP)-targeting radiopharmaceutical based on the
FAP-specific inhibitor (FAPI) is considered as a potential alternative agent to FDG for tumor …

Several recent studies comparing radiolabeled fibroblast activation protein inhibitors (FAPI)
and fluorine-18 fluorodeoxyglucose ([18F] F-FDG) as positron emission tomography (PET) …

Targeting cancer-associated fibroblasts (CAFs) has become an attractive goal for diagnostic
imaging and therapy because they can constitute as much as 90% of a tumor mass. The …