Microbiota in tumors: from understanding to application

Y Xie, F Xie, X Zhou, L Zhang, B Yang… - Advanced …, 2022 - Wiley Online Library
Microbes with complex functions have been found to be a potential component in tumor
microenvironments. Due to their low biomass and other obstacles, intratumor microbiota is …

[HTML][HTML] Intratumor microbiome in cancer progression: current developments, challenges and future trends

J Liu, Y Zhang - Biomarker Research, 2022 - Springer
Cancer is a complicated disease attributed to multifactorial changes, which causes
difficulties with treatment strategies. Various factors have been regarded as the main …

[HTML][HTML] Intratumor microbiota in cancer pathogenesis and immunity: from mechanisms of action to therapeutic opportunities

M Wang, F Yu, P Li - Frontiers in Immunology, 2023 - frontiersin.org
Microbial species that dwell human bodies have profound effects on overall health and
multiple pathological conditions. The tumor microenvironment (TME) is characterized by …

Influence of gut and intratumoral microbiota on the immune microenvironment and anti-cancer therapy

Y Chen, B Liu, Y Wei, DM Kuang - Pharmacological Research, 2021 - Elsevier
Microbiota has been implicated in the regulation of tumor progression and therapeutic
efficacy. However, the effect of microbiota on disease progression is context dependent …

[HTML][HTML] Broadening oncological boundaries: the intratumoral microbiota

YQ Lu, H Qiao, XR Tan, N Liu - Trends in Microbiology, 2024 - cell.com
The microbiota of solid tumors was identified> 100 years ago; however, heterogeneous
composition and diversity have been revealed only recently. Growing evidence has …

[HTML][HTML] Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

Unexpected guests in the tumor microenvironment: microbiome in cancer

A Wong-Rolle, HK Wei, C Zhao, C Jin - Protein & cell, 2021 - academic.oup.com
Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …

Emerging roles of intratumor microbiota in cancer metastasis

A Fu, B Yao, T Dong, S Cai - Trends in Cell Biology, 2023 - cell.com
Cancer metastasis is the leading cause of mortality in patients with cancer. Theories have
been developed to explain the causes and principles of metastasis. Metastasis is attributed …

[HTML][HTML] Clinical applications of gut microbiota in cancer biology

SH Wong, TNY Kwong, CY Wu, J Yu - Seminars in cancer biology, 2019 - Elsevier
The involvement of microorganisms in cancer has been increasing recognized. Collectively,
microorganisms have been estimated to account for∼ 20% of all cancers worldwide. Recent …

[HTML][HTML] Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …