[HTML][HTML] Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights
Nature has a nearly infinite inventory of unexplored phytochemicals and biomolecules that
have the potential to treat a variety of diseases. Safranal exhibits anti-cancer property and …
have the potential to treat a variety of diseases. Safranal exhibits anti-cancer property and …
[HTML][HTML] Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling
P Liu, SJ Atkinson, SE Akbareian, Z Zhou… - Scientific reports, 2017 - nature.com
Angiogenesis plays an important role in hepatocellular carcinoma (HCC), the inhibition of
which is explored for cancer prevention and treatment. The dietary phytochemical …
which is explored for cancer prevention and treatment. The dietary phytochemical …
[HTML][HTML] Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …
products and their derived biomolecules are potential resources to mine for novel anti …
Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades
Farnesiferol C (FC) is one of the major compounds isolated from Ferula assafoetida, an
Asian herbal spice used for cancer treatment as a folk remedy. Here, we examined the …
Asian herbal spice used for cancer treatment as a folk remedy. Here, we examined the …
Cryptotanshinone inhibits VEGF-induced angiogenesis by targeting the VEGFR2 signaling pathway
X Xu, L Wu, X Zhou, N Zhou, Q Zhuang, J Yang… - Microvascular …, 2017 - Elsevier
Objective Anti-angiogenesis has been proposed as an important strategy for angiogenesis-
related diseases. Cryptotanshinone (CPT), an active component of Salvia miltiorrhiza, may …
related diseases. Cryptotanshinone (CPT), an active component of Salvia miltiorrhiza, may …
Cinnamon extract reduces VEGF expression via suppressing HIF‐1α gene expression and inhibits tumor growth in mice
K Zhang, ES Han, TH Dellinger, J Lu… - Molecular …, 2017 - Wiley Online Library
Although many anti‐VEGF agents are available for cancer treatment, side effects of these
agents limit their application for cancer treatment and prevention. Here we studied the …
agents limit their application for cancer treatment and prevention. Here we studied the …
Antiangiogenic effects of flavonoids and chalcones
Angiogenesis, the development of new blood vessels from the existing vasculature, is
essential in normal developmental processes. Uncontrolled angiogenesis is a major …
essential in normal developmental processes. Uncontrolled angiogenesis is a major …
Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation by activating the Nrf2 pathway
L Qiu, L Hu, X Liu, W Li, X Zhang, H Xia, C Zhang - Food & Function, 2021 - pubs.rsc.org
Vascular intimal hyperplasia is a hallmark event in vascular restenosis. The excessive
proliferation, migration and phenotypic transformation of vascular smooth muscle cells …
proliferation, migration and phenotypic transformation of vascular smooth muscle cells …
Crocetin suppresses angiogenesis and metastasis through inhibiting sonic hedgehog signaling pathway in gastric cancer
M Zang, J Hou, Y Huang, J Wang, X Ding… - Biochemical and …, 2021 - Elsevier
Gastric cancer (GC) is one of the major causes of cancer-related deaths and
chemoresistance is a key obstacle to the treatment of GC, particularly in advanced GC. As …
chemoresistance is a key obstacle to the treatment of GC, particularly in advanced GC. As …
[PDF][PDF] Webba Da Silva, M.; McCarron, PA; Tambuwala, MM Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways. Cells …
Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …