Current strategies for targeted delivery of bio-active drug molecules in the treatment of brain tumor

T Garg, S Bhandari, G Rath, AK Goyal - Journal of drug targeting, 2015 - Taylor & Francis
Brain tumor is one of the most challenging diseases to treat. The major obstacle in the
specific drug delivery to brain is blood–brain barrier (BBB). Mostly available anti-cancer …

Advances in targeted drug delivery approaches for the central nervous system tumors: the inspiration of nanobiotechnology

J Meng, V Agrahari, I Youm - Journal of Neuroimmune Pharmacology, 2017 - Springer
At present, brain tumor is among the most challenging diseases to treat and the therapy is
limited by the lack of effective methods to deliver anticancer agents across the blood-brain …

Combinatorial therapeutic strategies for enhanced delivery of therapeutics to brain cancer cells through nanocarriers: current trends and future perspectives

X Wang, C Wu, S Liu, D Peng - Drug Delivery, 2022 - Taylor & Francis
Brain cancer is the most aggressive one among various cancers. It has a drastic impact on
people's lives because of the failure in treatment efficacy of the currently employed …

Novel nano-drug delivery system for brain tumor treatment

Z Qiu, Z Yu, T Xu, L Wang, N Meng, H Jin, B Xu - Cells, 2022 - mdpi.com
As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Beyond the blood–brain barrier: facing new challenges and prospects of nanotechnology-mediated targeted delivery to the brain

M Kumar, P Sharma, R Maheshwari, M Tekade… - … -Based Targeted Drug …, 2018 - Elsevier
The blood–brain barrier (BBB) is a stealth barrier that protects the brain, and allows the entry
of only a select pool of compounds into the brain and functions towards the maintenance of …

Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy

L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

[HTML][HTML] Progress and perspectives on targeting nanoparticles for brain drug delivery

H Gao - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Nanobiotechnology-based strategies for crossing the blood–brain barrier

KK Jain - Nanomedicine, 2012 - Taylor & Francis
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it
also significantly hinders the delivery of therapeutics to the brain. Several strategies have …

[图书][B] Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

P Kesharwani, U Gupta - 2018 - books.google.com
Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain
anatomy and tumors and the progress and challenges in delivering drugs across the blood …