Background Hyaluronic acid has been extensively used for treatment of knee osteoarthritis
due to its anti-inflammatory properties and its ability to act as a synovial lubricant …

Osteoarthritis is characterized by progressive articular cartilage degeneration, changes in
subchondral bone and synovial inflammation, leading to pain and disability …

Aim To evaluate the therapeutic trajectory of intra‐articular injections of hyaluronic acid at
high concentration (2%) performed at 4‐month intervals. Methods Subjects with knee …

Introduction The objective of this study was to compare a single intra-articular injection of an
innovative high and low molecular weight hyaluronic acid formulation (HA-HL) versus …

Abstract Treatment with intra-articular viscosupplementation with hyaluronan (hyaluronic
acid) and its derivatives is an important component of the management of osteoarthritis (OA) …

The safety and efficacy of Hyruan ONE (test product), an intra-articular cross-linked sodium
hyaluronate injection, to treat mild-to-moderate knee osteoarthritis was compared with that of …

Efficacy and safety of high and low molecular weight hyaluronates in knee osteoarthritis
patients were compared in a randomized, open-label trial. Patients in the high molecular …

Osteoarthritis (OA) is the most common form of chronic arthritis worldwide. The etiology of
pain in osteoarthritis is multifactoral, and includes mechanical and inflammatory processes …

Purpose The primary objective was to demonstrate the safety and effectiveness of
Monovisc™ in the relief of joint pain in patients with idiopathic knee OA compared to saline …

Objective We performed a meta-analysis of randomized controlled trials (RCTs) to compare
the efficacy and safety of intra-articular methylprednisolone and hyaluronic acid (HA) in term …