Objective This study aimed to explore shared genetic etiology and the causality between
smoking status and type 2 diabetes (T2D), cardiovascular diseases (CVDs), and related …

Smoking is a potentially causal behavioral risk factor for type 2 diabetes (T2D), but not all
smokers develop T2D. It is unknown whether genetic factors partially explain this variation …

Background Previous observational studies have shown an association between smoking
and coronary artery disease (CAD) in patients with diabetes. Whether this association …

The causality between smoking and type 2 diabetes is unclear. We conducted a two-sample
Mendelian randomization study to explore the causal relationship between smoking …

Background Smokers are at increased risk of type 2 diabetes (T2D), but the underlying
mechanisms are unclear. We investigated if the smoking-T2D association is mediated by …

Clinical observations have linked tobacco smoking with increased type 2 diabetes risk.
Mendelian randomization analysis has recently suggested smoking may be a causal risk …

Background This study explores the intricate relationship between smoking, cardiovascular
disease (CVD) risk factors and their combined impact on overall CVD risk, utilizing data from …

The large-scale genome-wide association studies conducted so far identified numerous
allelic variants associated with type 2 diabetes (T2D), coronary heart disease (CHD) and …

Mehta Genomics of Type 2 Diabetes 709 variants associated with body mass index (CEU
r2= 0.80) and triglyceride concentration (CEU r2= 0.84) and has been associated with waist …

Though both genetic and lifestyle factors are known to influence cardiometabolic outcomes,
less attention has been given to whether lifestyle exposures can alter the association …