[HTML][HTML] PRAK, a novel protein kinase regulated by the p38 MAP kinase
L New, Y Jiang, M Zhao, K Liu, W Zhu, LJ Flood… - The EMBO …, 1998 - embopress.org
We have identified and cloned a novel serine/threonine kinase, p38‐regulated/activated
protein kinase (PRAK). PRAK is a 471 amino acid protein with 20–30% sequence identity to …
protein kinase (PRAK). PRAK is a 471 amino acid protein with 20–30% sequence identity to …
SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases
S Mertens, M Craxton, M Goedert - FEBS letters, 1996 - Elsevier
Stress-activated protein kinases are MAP kinase homologues that are activated by cellular
stresses, bacterial endotoxin and inflammatory cytokines. They are activated by a dual …
stresses, bacterial endotoxin and inflammatory cytokines. They are activated by a dual …
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
J Rouse, P Cohen, S Trigon, M Morange… - Cell, 1994 - cell.com
Summary MAPK-activated protein kinase-2 (MAPKAP kinase-2) is activated in vitro by the
p42 and p44 isoforms of MAPK (p42/p44-). In several cell lines, however, MAPKAP kinase-2 …
p42 and p44 isoforms of MAPK (p42/p44-). In several cell lines, however, MAPKAP kinase-2 …
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress‐and cytokine‐stimulated monocytes and epithelial cells.
A Cuenda, G Alonso, N Morrice, M Jones… - The EMBO …, 1996 - embopress.org
Two chromatographically distinct stress‐activated protein kinase kinases (SAPKKs) have
been identified in several mammalian cells, termed SAPKK2 and SAPKK3, which activate …
been identified in several mammalian cells, termed SAPKK2 and SAPKK3, which activate …
Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27
J Guay, H Lambert, G Gingras-Breton… - Journal of cell …, 1997 - journals.biologists.com
We have studied the contribution of the individual kinases of the MAP (mitogen-activated
protein) kinase family, including ERK (extracellular-signal regulated kinase), JNK/SAPK (c …
protein) kinase family, including ERK (extracellular-signal regulated kinase), JNK/SAPK (c …
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine (∗)
J Raingeaud, S Gupta, JS Rogers, M Dickens… - Journal of Biological …, 1995 - ASBMB
Protein kinases activated by dual phosphorylation on Tyr and Thr (MAP kinases) can be
grouped into two major classes: ERK and JNK. The ERK group regulates multiple targets in …
grouped into two major classes: ERK and JNK. The ERK group regulates multiple targets in …
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase
MM McLaughlin, S Kumar, PC McDonnell… - Journal of Biological …, 1996 - ASBMB
CSBP p38 is a mitogen-activated protein kinase that is activated in response to stress,
endotoxin, interleukin 1, and tumor necrosis factor. Using a catalytically inactive mutant …
endotoxin, interleukin 1, and tumor necrosis factor. Using a catalytically inactive mutant …
MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27
C Zheng, Z Lin, ZJ Zhao, Y Yang, H Niu… - Journal of Biological …, 2006 - ASBMB
The p38 MAPK and heat shock protein 27 (hsp27) form a signaling complex with
serine/threonine kinase Akt and MAPK-activated protein kinase-2 (MK2), which plays an …
serine/threonine kinase Akt and MAPK-activated protein kinase-2 (MK2), which plays an …
Regulation of PRAK subcellular location by p38 MAP kinases
L New, Y Jiang, J Han - Molecular biology of the cell, 2003 - Am Soc Cell Biol
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in
cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated …
cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated …
[HTML][HTML] Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of …
Abstract Stress‐activated protein kinase‐3 (SAPK3), a recently described MAP kinase family
member with a widespread tissue distribution, was transfected into several mammalian cell …
member with a widespread tissue distribution, was transfected into several mammalian cell …