[HTML][HTML] Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney

Q Chen, Y Nan, Y Yang, Z Xiao, M Liu, J Huang… - Bioactive materials, 2023 - Elsevier
Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the
high prevalence and high mortality rate of AKI, the development of drugs to effectively treat …

Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury

L Li, Y Shen, Z Tang, Y Yang, Z Fu, D Ni, X Cai - Exploration, 2023 - Wiley Online Library
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal
function, and is associated with a high risk of death. Many pathological changes happen in …

Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury

Y Wang, H Jiang, L Zhang, P Yao, S Wang… - … in Bioengineering and …, 2023 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome that results from a rapid decline in renal
structure or renal functional impairment with the main pathological feature of sublethal and …

[HTML][HTML] Recent advances in nanotherapeutics for the treatment and prevention of acute kidney injury

H Yu, D Liu, G Shu, F Jin, Y Du - Asian journal of pharmaceutical sciences, 2021 - Elsevier
Acute kidney injury (AKI) is a serious kidney disease without specific medications currently
except for expensive dialysis treatment. Some potential drugs are limited due to their high …

Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives

HN Geo, DD Murugan, Z Chik, A Norazit, YY Foo… - Journal of Controlled …, 2022 - Elsevier
Acute kidney injury (AKI) causes considerable morbidity and mortality, particularly in the
case of post-cardiac infarction or kidney transplantation; however, the site-specific …

Application of nanotechnology in acute kidney injury: From diagnosis to therapeutic implications

Y Zhao, M Pu, Y Wang, L Yu, X Song, Z He - Journal of Controlled Release, 2021 - Elsevier
Acute kidney injury (AKI), a major health issue concerning~ 50% of patients treated in
intensive care units, generally leads to severe renal damage associated with high mortality …

Phenylenediamine-based carbon nanodots alleviate acute kidney injury via preferential renal accumulation and antioxidant capacity

J Gao, Y Liu, B Jiang, W Cao, Y Kan… - … applied materials & …, 2020 - ACS Publications
As a reactive oxygen species (ROS)-promoted disease, acute kidney injury (AKI) is
associated with high mortality and morbidity, but no effective pharmacological treatment is …

Renoprotective approaches and strategies in acute kidney injury

Y Yang, M Song, Y Liu, H Liu, L Sun, Y Peng… - Pharmacology & …, 2016 - Elsevier
Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …

Antioxidative 0-dimensional Nanodrugs Overcomes Obstacles in AKI Antioxidant Therapy

Y Yang, Y Nan, Q Chen, Z Xiao, H Zhang… - Journal of Materials …, 2023 - pubs.rsc.org
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to enormous health risks and …

Small molecules as a source for acute kidney injury therapy

YL Feng, Y Yang, H Chen - Pharmacology & therapeutics, 2022 - Elsevier
Acute kidney injury (AKI) is a sudden loss of kidney function that causes a rise in serum
creatinine and a decrease in urine output, which leads to high morbidity and mortality …