[HTML][HTML] Extracellular vesicles derived from human adipose-derived stem cells promote the exogenous angiogenesis of fat grafts via the let-7/AGO1/VEGF signalling …

Y Zhu, J Zhang, X Hu, Z Wang, S Wu, Y Yi - Scientific reports, 2020 - nature.com
Extracellular vesicles (EVs) derived from human adipose-derived stem cells (hADSCs)
possess the proangiogenic potential for ischaemic diseases. Thus, our study aimed to …

[HTML][HTML] Microvesicles (MIVs) secreted from adipose-derived stem cells (ADSCs) contain multiple microRNAs and promote the migration and invasion of endothelial …

B Huang, LF Huang, L Zhao, Z Zeng, X Wang, D Cao… - Genes & diseases, 2020 - Elsevier
Extracellular vesicles (EVs) such as microvesicles (MIVs) play an important role in
intercellular communications. MIVs are small membrane vesicles sized 100–1000 nm in …

[HTML][HTML] Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential

T Lopatina, S Bruno, C Tetta, N Kalinina… - Cell Communication and …, 2014 - Springer
Background Several studies demonstrate the role of adipose mesenchymal stem cells
(ASCs) in angiogenesis. The angiogenic mechanism has been ascribed to paracrine factors …

[HTML][HTML] Angiogenic effects and crosstalk of adipose-derived mesenchymal stem/stromal cells and their extracellular vesicles with endothelial cells

S Rautiainen, T Laaksonen, R Koivuniemi - International Journal of …, 2021 - mdpi.com
Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Exosomes derived from hypoxia-treated human adipose mesenchymal stem cells enhance angiogenesis through the PKA signaling pathway

C Xue, Y Shen, X Li, B Li, S Zhao, J Gu… - Stem cells and …, 2018 - liebertpub.com
Angiogenesis is a complicated and sequential process that plays an important role in
different physiological processes. Mesenchymal stem cells (MSCs), which are pluripotent …

Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R

Y Han, J Ren, Y Bai, X Pei, Y Han - … journal of biochemistry & cell biology, 2019 - Elsevier
Background We previously reported that co-transplantation of exosomes from hypoxia-
preconditioned adipose mesenchymal stem cells (ADSCs) improves the neoangiogenesis …

[HTML][HTML] Nano-sized extracellular vesicles secreted from GATA-4 modified mesenchymal stem cells promote angiogenesis by delivering Let-7 miRNAs

M Gong, M Wang, J Xu, B Yu, YG Wang, M Liu… - Cells, 2022 - mdpi.com
We demonstrated previously that extracellular vesicles (EVs) released from mesenchymal
stem cells (MSCs) play a critical role in angiogenesis. Here, we examine whether this pro …

[HTML][HTML] Obesity reduces the pro-angiogenic potential of adipose tissue stem cell-derived extracellular vesicles (EVs) by impairing miR-126 content: impact on clinical …

G Togliatto, P Dentelli, M Gili, S Gallo… - International journal of …, 2016 - nature.com
Methods: ASCs were recovered from 10 obese (oASCs) and 6 non-obese (nASCs)
participants and characterized. In selected experiments, nASCs and oASCs were cultured …

Adipose-derived stem cells induce angiogenesis via microvesicle transport of miRNA-31

T Kang, TM Jones, C Naddell… - Stem cells …, 2016 - academic.oup.com
Cell secretion is an important mechanism for stem cell-based therapeutic angiogenesis,
along with cell differentiation to vascular endothelial cells or smooth muscle cells. Cell …

[HTML][HTML] Exosomal miR-423-5p mediates the proangiogenic activity of human adipose-derived stem cells by targeting Sufu

F Xu, Q Xiang, J Huang, Q Chen, N Yu, X Long… - Stem cell research & …, 2019 - Springer
Background Human adipose-derived stem cells (hADSCs) are an important source of cells
for regenerative medicine. Evidence of extensive interactions with the surrounding …