Recent years have seen a profound resurgence of activity with nonhuman primates (NHPs)
to model human brain disorders. From marmosets to macaques, the study of NHP species …

Although everyone would agree that successful translation of therapeutic candidates for
central nervous disorders should involve non-human primate (nhp) models of cognitive …

Highlights•Genome editing technologies have made it feasible to generate genetically
modified NHP models.•Genetic NHP models have certain advantages to study higher brain …

The prevalence and societal impact of neurodevelopmental disorders (NDDs) continue to
increase despite years of research in both patient populations and animal models. There …

Rodents have been the principal model to study brain anatomy and function due to their well-
mapped brain architecture, rapid reproduction and amenability to genetic modification …

Lesioning and neurophysiological studies have facilitated the elucidation of cortical
functions and mechanisms of functional recovery following injury. Clinical translation of such …

Neuroscience is progressively increasing its comprehension of the normal functioning of the
central and peripheral nervous system. Such understanding is essential to challenge …

The two most common neurological disorders of the basal ganglia are Parkinson's disease
(PD) and Huntington's disease (HD). The most overt symptoms of these diseases are …

Neurodegenerative diseases (NDs) are a group of debilitating neurological disorders that
primarily affect elderly populations and include Alzheimer's disease (AD), Parkinson's …

The realm of human uniqueness steadily shrinks; reflecting this, other primates suffer from
states closer to depression or anxiety than'depressive-like'or'anxiety-like behavior' …