Outer retinal tubulation in advanced age-related macular degeneration: optical coherence tomographic findings correspond to histology

KB Schaal, KB Freund, KM Litts, Y Zhang… - Retina, 2015 - journals.lww.com
Purpose: To compare optical coherence tomography (OCT) and histology of outer retinal
tubulation (ORT) secondary to advanced age-related macular degeneration in patients and …

Quantitative analysis of outer retinal tubulation in age-related macular degeneration from spectral-domain optical coherence tomography and histology

KM Litts, T Ach, KM Hammack… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: To assess outer retinal tubulation (ORT) morphology from spectral-domain optical
coherence tomography (SD-OCT) volumes and donor eye histology, analyze ORT …

Outer retinal tubulation in degenerative retinal disorders

NR Goldberg, JP Greenberg, K Laud, S Tsang… - Retina, 2013 - journals.lww.com
Purpose: To demonstrate outer retinal tubulation (ORT) in various degenerative retinal
disorders. Methods: This was a retrospective review of the multimodal imaging of 29 eyes of …

Outer retinal tubulation: a novel optical coherence tomography finding

SA Zweifel, M Engelbert, K Laud… - Archives of …, 2009 - jamanetwork.com
Objective To describe tubular structures found in the outer retina seen in a variety of retinal
disorders. Methods Sixty-nine eyes of 63 patients were examined with spectral-domain …

[HTML][HTML] Inner segment remodeling and mitochondrial translocation in cone photoreceptors in age-related macular degeneration with outer retinal tubulation

KM Litts, JD Messinger, KB Freund… - … & visual science, 2015 - jov.arvojournals.org
Purpose.: To quantify impressions of mitochondrial translocation in degenerating cones and
to determine the nature of accumulated material in the subretinal space with apparent inner …

Optical coherence tomography analysis of outer retinal tubulations: sequential evolution and pathophysiological insights

RC Preti, A Govetto, RG Aqueta Filho, LC Zacharias… - Retina, 2018 - journals.lww.com
Purpose: To describe the sequential evolution of outer retinal tubulations (ORTs) in patients
diagnosed with choroidal neovascularization and/or retinal pigment epithelium atrophy …

Outer retinal tubulation in inherited retinal degenerative disease

A Iriyama, Y Aihara, Y Yanagi - Retina, 2013 - journals.lww.com
Purpose: To investigate the prevalence and characteristics of outer retinal tubulation (ORT)
seen in inherited retinal degenerative diseases. Methods: A total of 354 eyes of 177 patients …

The evolution of outer retinal tubulation, a neurodegeneration and gliosis prominent in macular diseases

R Dolz-Marco, KM Litts, ACS Tan, KB Freund… - Ophthalmology, 2017 - Elsevier
Purpose To document outer retinal tubulation (ORT) formation in advanced retinal disorders.
Design Retrospective, observational study. Participants Consecutive cases with retinal …

Optical coherence tomography and histology of age-related macular degeneration support mitochondria as reflectivity sources

KM Litts, Y Zhang, KB Freund, CA Curcio - Retina, 2018 - journals.lww.com
Purpose: Widespread adoption of optical coherence tomography has revolutionized the
diagnosis and management of retinal disease. If the cellular and subcellular sources of …

Outer retinal tubulation in the comparison of age-related macular degeneration treatments trials (CATT)

JY Lee, FA Folgar, MG Maguire, G Ying, CA Toth… - Ophthalmology, 2014 - Elsevier
Purpose To determine the prevalence of, risk factors for, and visual acuity (VA) correlations
with outer retinal tubulation (ORT) seen on spectral-domain optical coherence tomography …