Recent advances in organocatalytic glycosylations

R Williams, MC Galan - European Journal of Organic Chemistry, 2017 - Wiley Online Library
Carbohydrates play a pivotal role in biological systems and present an opportunity to
develop potent carbohydrate‐derived therapeutics and diagnostic tools for the treatment and …

New chemical processes to streamline carbohydrate synthesis

KJ Li, CS Bennett - Current Opinion in Chemical Biology, 2022 - Elsevier
Carbohydrates hold potential for the future of therapeutic development due to their important
role in essential biological processes. However, it is still challenging to produce …

Glycosylation via Transition‐Metal Catalysis: Challenges and Opportunities

X Li, J Zhu - European Journal of Organic Chemistry, 2016 - Wiley Online Library
Development of efficient, mild, and easily operable stereoselective glycosylations is of
critical importance to access sufficient amounts of pure and structurally well‐defined …

Organocatalysis applied to carbohydrates: from roots to current developments

F Gallier, LSM e Miranda - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Organocatalysis emerged in the last decade as a powerful tool for the synthesis of complex
molecules. In the field of carbohydrates, it found widespread use in the synthesis of rare and …

Enzymatic synthesis of oligosaccharides: a powerful tool for a sweet challenge

M Filice, M Marciello - Current Organic Chemistry, 2013 - ingentaconnect.com
Carbohydrates are complex and structurally diverse compounds in nature with key roles in a
broad range of life processes including signal transduction, carcinogenesis and immune …

Recent advances in transition metal-catalyzed glycosylation

MJ McKay, HM Nguyen - ACS catalysis, 2012 - ACS Publications
Having access to mild and operationally simple techniques for attaining carbohydrate
targets will be necessary to facilitate advancement in biological, medicinal, and …

Ligand-controlled, transition-metal catalyzed site-selective modification of glycosides

W Shang, B He, D Niu - Carbohydrate research, 2019 - Elsevier
Carbohydrates play important roles in many physiological and pathological events. The
preparation of the derivatives and conjugates of carbohydrates is often needed to help …

Recent developments in stereoselective chemical glycosylation

J Ling, CS Bennett - Asian journal of organic chemistry, 2019 - Wiley Online Library
Because of their pivotal biological functions, attention to sugars and glycobiology has grown
rapidly in recent decades, leading to increased demand for homogeneous oligosaccharides …

Catalytic glycosylations in oligosaccharide synthesis

MM Nielsen, CM Pedersen - Chemical reviews, 2018 - ACS Publications
Catalytic glycosylation has been a central reaction in carbohydrate chemistry since its
introduction by Fischer 125 years ago, but it is only in the past three to four decades that …

[HTML][HTML] Regioselective modification of unprotected glycosides

M Jäger, AJ Minnaard - Chemical Communications, 2016 - pubs.rsc.org
Selective modification of unprotected carbohydrates is difficult due to the similar reactivity of
the hydroxyl groups. In carbohydrate synthesis, therefore, even straightforward …