SmartPill™ administration to assess gastrointestinal function after spinal cord injury in a porcine model—a preliminary study

CA Knibbe, RU Ahmed, F Wilkins, M Sharma… - Biomedicines, 2023 - mdpi.com
Gastrointestinal (GI) complications, including motility disorders, metabolic deficiencies, and
changes in gut microbiota following spinal cord injury (SCI), are associated with poor …

SmartPill technology provides safe and effective assessment of gastrointestinal function in persons with spinal cord injury

RE Williams, WA Bauman, AM Spungen, RR Vinnakota… - Spinal Cord, 2012 - nature.com
Study design: Spinal cord injury (SCI) results in gastrointestinal (GI) complications, including
gastroesophageal reflux disease and constipation, but much of the data is based on older …

Investigation of microbiota alterations and intestinal inflammation post-spinal cord injury in rat model

G O'Connor, E Jeffrey, D Madorma, A Marcillo… - Journal of …, 2018 - liebertpub.com
Although there has been a significant amount of research focused on the pathophysiology of
spinal cord injury (SCI), there is limited information on the consequences of SCI on remote …

Spinal cord injury and gut microbiota: A review

Y Jing, F Bai, Y Yu - Life Sciences, 2021 - Elsevier
After spinal cord injury (SCI), intestinal dysfunction has a serious impact on physical and
mental health, quality of life, and social participation. Recent data from rodent and human …

Upper gastrointestinal motility changes following spinal cord injury

FAA Gondim, GR De Oliveira… - Neurogastroenterology …, 2010 - Wiley Online Library
Spinal cord injury (SCI) is associated with severe autonomic dysfunction in both the acute
and chronic phases. Upper gastrointestinal (GI) motor dysfunction has been previously …

[HTML][HTML] Gut microbiota are disease-modifying factors after traumatic spinal cord injury

KA Kigerl, K Mostacada, PG Popovich - Neurotherapeutics, 2018 - Elsevier
Spinal cord injury (SCI) disrupts the autonomic nervous system (ANS), impairing its ability to
coordinate organ function throughout the body. Emerging data indicate that the systemic …

Neural and anatomical abnormalities of the gastrointestinal system resulting from contusion spinal cord injury

S Kabatas, D Yu, XD He, HS Thatte, D Benedict… - Neuroscience, 2008 - Elsevier
Gastrointestinal (GI) abnormalities resulting from spinal cord injury (SCI) are challenging
disorders that have not been examined experimentally using clinically relevant models. In …

Melatonin treatment alleviates spinal cord injury-induced gut dysbiosis in mice

Y Jing, D Yang, F Bai, C Zhang, C Qin, D Li… - Journal of …, 2019 - liebertpub.com
Spinal cord injury (SCI) disturbs the autonomic nervous system and induces dysfunction in
multiple organs/tissues, such as the gastrointestinal (GI) system. The neuroprotective effects …

Intestinal microbiota and melatonin in the treatment of secondary injury and complications after spinal cord injury

Y Zhang, R Lang, S Guo, X Luo, H Li, C Liu… - Frontiers in …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a central nervous system (CNS) disease that can cause sensory
and motor impairment below the level of injury. Currently, the treatment scheme for SCI …

Spinal cord–gut–immune axis and its implications regarding therapeutic development for spinal cord injury

KD Pawlowski, BT David, RG Fessler - Journal of Neurotrauma, 2023 - liebertpub.com
Spinal cord injury (SCI) affects∼ 1,300,000 people living in the United States. Most research
efforts have been focused on reversing paralysis, as this is arguably the most defining …