Non-identical twins: Different faces of CR3 and CR4 in myeloid and lymphoid cells of mice and men

A Erdei, S Lukácsi, B Mácsik-Valent… - Seminars in cell & …, 2019 - Elsevier
Integrins are cell membrane receptors that are involved in essential physiological and
serious pathological processes. Their main role is to ensure a closely regulated link …

The role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in complement-mediated phagocytosis and podosome formation by human phagocytes

S Lukácsi, Z Nagy-Baló, A Erdei, N Sándor, Z Bajtay - Immunology letters, 2017 - Elsevier
CR3 and CR4 belong to the family of β 2-integrins and play an important role in
phagocytosis, cellular adherence and migration. CR3 and CR4 are generally expected to …

[HTML][HTML] Structural immunology of complement receptors 3 and 4

T Vorup-Jensen, RK Jensen - Frontiers in immunology, 2018 - frontiersin.org
Complement receptors (CR) 3 and 4 belong to the family of beta-2 (CD18) integrins. CR3
and CR4 are often co-expressed in the myeloid subsets of leukocytes, but they are also …

[HTML][HTML] New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR4

A Erdei, KG Kovács, Z Nagy-Baló, S Lukácsi… - Immunology …, 2021 - Elsevier
The involvement of complement in the regulation of antibody responses has been known for
long. By now several additional B cell functions–including cytokine production and antigen …

Functions of α4-and β7-integrins in hematopoiesis, lymphocyte trafficking and organ development

N Wagner, W Müller - Leukocyte Integrins in the Immune System and …, 1998 - Springer
The family of integrins comprise more than 20 αβ (3 heterodimeric membrane bound
glycoproteins that mediate cell-cell and cell-extracellular matrix contacts. To date, 16 α and …

Complement receptor 2 in the regulation of the immune response

M Tolnay, GC Tsokos - Clinical immunology and immunopathology, 1998 - Elsevier
Antigens coated with split products of C3, the result of complement activation, are capable of
crosslinking the complement receptor 2 (CR2, CD21) and the antigen receptor on the …

CR3 (CD11b/CD18) expressed by cytotoxic T cells and natural killer cells is upregulated in a manner similar to neutrophil CR3 following stimulation with various …

S Muto, V Větvička, GD Ross - Journal of clinical immunology, 1993 - Springer
Abstract CR3 (CD11b/CD18) functions both as an iC3b-receptor and as an adhesion
molecule for cellular ligands such as ICAM-1. Although CR3 has been well characterized on …

[HTML][HTML] CR3 is the dominant phagocytotic complement receptor on human dendritic cells

N Sándor, K Kristóf, K Paréj, D Pap, A Erdei, Z Bajtay - Immunobiology, 2013 - Elsevier
Dendritic cells (DCs) play a decisive role in immunity; they interact with various pathogens
via several pattern recognition and different opsonophagocytotic receptors, including Fc-and …

[HTML][HTML] The promiscuous profile of complement receptor 3 in ligand binding, immune modulation, and pathophysiology

C Lamers, CJ Plüss, D Ricklin - Frontiers in immunology, 2021 - frontiersin.org
The β 2-integrin receptor family has a broad spectrum of physiological functions ranging
from leukocyte adhesion, cell migration, activation, and communication to the phagocytic …

Receptor-receptor interactions of complement receptor type 3 in neutrophil membranes

HR Petty, RR Todd - Journal of Leucocyte Biology, 1993 - academic.oup.com
The leukocyte integrin CR3 (GDllb/CD18) is known to participate in a variety of cell
functions. Recent studies have indicated that CR3 may communicate with other plasma …