Polyamines are small organic polycations that are absolutely required for cell growth and
proliferation; yet the basis for this requirement is mostly unknown. Here, we combined a …

Polyamines are aliphatic cations with multiple functions and are essential for life. Cellular
polyamine levels are regulated by multiple pathways such as synthesis from amino acid …

The polyamines spermidine and spermine and their precursor putrescine are intimately
involved in and are required for cell growth and proliferation. This study examines the …

The polyamines (PAs) spermidine, spermine, putrescine and cadaverine are an essential
class of metabolites found throughout all kingdoms of life. In this comprehensive review, we …

Polyamines are important multifunctional cellular components and are classically
considered as mediators of cell growth and division. Recently polyamines have been also …

The cell cycle regulatory events that interface with polyamine requirements for cell growth
have not yet been clearly identified. Here we use specific inhibitors of polyamine …

Polyamines are small organic cations that are essential for normal cell growth and
development in eukaryotes. Under normal physiological conditions, intracellular polyamine …

• Introduction• Metabolism and transport of physiological polyamines• Are physiological
polyamines stress molecules?• Roles of physiological polyamines in oxidative stress …

Polyamines (PAs) are essential organic polycations for cell viability along the whole
phylogenetic scale. In mammals, they are involved in the most important physiological …

Polyamines, namely putrescine, spermidine, and spermine, are essential for cell survival
and proliferation. A decrease in intracellular polyamine levels is associated with apoptosis …