Liver disease is a significant health challenge worldwide and comprises liver fibrosis and
cirrhosis, viral hepatitis, fatty liver, non‑alcoholic fatty liver disease, alcoholic liver disease …

Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent and slow progressing hepatic
pathology characterized by different stages of increasing severity which can ultimately give …

Results S100 genes display a complex expression pattern in colorectal and hepatocel lular
carcinoma. They are expressed in tumor and/or tumor stroma cells, and they exert both pro …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca (2)+ …

The S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-
hand structures, that is, helix-loop-helix motifs specialized in high-affinity calciumbinding …

The S100 family proteins possess a variety of intracellular and extracellular functions. They
interact with multiple receptors and signal transducers to regulate pathways that govern …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Proteins in S100 family exhibit different expressions patterns and perform different
cytological functions, playing substantial roles in certain cancers, carcinogenesis, and …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …

The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …