MicroRNAs (miRNAs) are important post-transcriptional regulators of nearly every biological
process in the cell and play key roles in the pathogenesis of human disease. As a result …

MicroRNAs (miRNAs) are short noncoding RNAs, which bind to messenger RNAs and
regulate protein expression. The biosynthesis of miRNAs includes two precursors, a primary …

Background The stability and propagation of hepatitis C virus (HCV) is dependent on a
functional interaction between the HCV genome and liver-expressed microRNA-122 (miR …

MicroRNA 122 (miR-122) is liver specific, fine-tunes lipid metabolism, and is required for
hepatitis C virus (HCV) abundance. Miravirsen, an oligonucleotide with locked nucleic acid …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate the expression of a large
fraction of genes in animals, plants, and protozoa. miRNA-mediated gene repression occurs …

Ten years after Fire and Melo's Nobel Prize for discovery of gene silencing by double-
stranded RNA, a remarkable progress was achieved in RNA interference (RNAi). Changes …

In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …

MiRNAs are a conserved class of non-coding RNAs that negatively regulate gene
expression post-transcriptionally. Although their biological roles are largely unknown …

MicroRNA molecules (miRNAs) are naturally occurring triggers of the RNA-interference
pathway. The first identified miRNA, lin-4, was discovered in Caenorhabditis elegans> 20 …

• Introduction‐Brief history, biogenesis and the regulated mechanism of miRNAs• Roles of
miRNAs in human disease and miRNAs as a novel biomarker for cancer and disease …