Safety and efficacy of single-dose Ad26. COV2. S vaccine against Covid-19

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2021 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine is a recombinant, replication-incompetent
human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome …

Interim results of a phase 1–2a trial of Ad26. COV2. S Covid-19 vaccine

J Sadoff, M Le Gars, G Shukarev… - … England Journal of …, 2021 - Mass Medical Soc
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …

Safety and immunogenicity of the Ad26. COV2. S COVID-19 vaccine candidate: interim results of a phase 1/2a, double-blind, randomized, placebo-controlled trial

J Sadoff, ML Gars, G Shukarev, D Heerwegh, C Truyers… - MedRxiv, 2020 - medrxiv.org
ABSTRACT BACKGROUND The ongoing coronavirus disease (COVID)-19 pandemic
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be …

Final analysis of efficacy and safety of single-dose Ad26. COV2. S

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine was highly effective against severe–
critical coronavirus disease 2019 (Covid-19), hospitalization, and death in the primary phase …

Efficacy, safety, and immunogenicity of a booster regimen of Ad26. COV2. S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo …

K Hardt, A Vandebosch, J Sadoff, M Le Gars… - The Lancet Infectious …, 2022 - thelancet.com
Background Despite the availability of effective vaccines against COVID-19, booster
vaccinations are needed to maintain vaccine-induced protection against variant strains and …

Immunogenicity of the Ad26. COV2. S Vaccine for COVID-19

KE Stephenson, M Le Gars, J Sadoff, AM de Groot… - Jama, 2021 - jamanetwork.com
Importance Control of the global COVID-19 pandemic will require the development and
deployment of safe and effective vaccines. Objective To evaluate the immunogenicity of the …

[HTML][HTML] Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first …

FC Zhu, YH Li, XH Guan, LH Hou, WJ Wang, JX Li… - The Lancet, 2020 - thelancet.com
Background A vaccine to protect against COVID-19 is urgently needed. We aimed to assess
the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) …

Analysis of the effectiveness of the Ad26. COV2. S adenoviral vector vaccine for preventing COVID-19

J Corchado-Garcia, D Zemmour, T Hughes… - JAMA network …, 2021 - jamanetwork.com
Importance Continuous assessment of the effectiveness and safety of the US Food and Drug
Administration–authorized SARS-CoV-2 vaccines is critical to amplify transparency, build …

Ad26. COV2. S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

JEM van Der Lubbe, SK Rosendahl Huber, A Vijayan… - npj Vaccines, 2021 - nature.com
Previously we have shown that a single dose of recombinant adenovirus serotype 26 (Ad26)
vaccine expressing a prefusion stabilized SARS-CoV-2 spike antigen (Ad26. COV2. S) is …

[HTML][HTML] Efficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a randomised, double-blind, controlled …

R Ella, S Reddy, W Blackwelder, V Potdar, P Yadav… - The Lancet, 2021 - thelancet.com
Background We report the clinical efficacy against COVID-19 infection of BBV152, a whole
virion inactivated SARS-CoV-2 vaccine formulated with a toll-like receptor 7/8 agonist …