Long non-coding RNAs: a novel paradigm for toxicology

JL Dempsey, JY Cui - Toxicological Sciences, 2017 - academic.oup.com
Long non-coding RNAs (lncRNAs) are over 200 nucleotides in length and are transcribed
from the mammalian genome in a tissue-specific and developmentally regulated pattern …

Long noncoding RNAs: emerging stars in gene regulation, epigenetics and human disease

A Bhan, SS Mandal - ChemMedChem, 2014 - Wiley Online Library
Noncoding RNAs (ncRNAs) are classes of transcripts that are encoded by the genome and
transcribed but never get translated into proteins. Though not translated into proteins …

Physiological roles of long noncoding RNAs: insight from knockout mice

L Li, HY Chang - Trends in cell biology, 2014 - cell.com
Long noncoding RNAs (lncRNAs) are a pervasive and recently recognized class of genes.
lncRNAs have been proposed to modulate gene expression and nuclear architecture, but …

Dysregulations of long non-coding RNAs− the emerging “lnc” in environmental carcinogenesis

PS Wang, Z Wang, C Yang - Seminars in cancer biology, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) refer to a class of RNA molecules that are more than 200
nucleotides in length and usually lack protein-coding capacity. LncRNAs play important …

Long noncoding RNA: its physiological and pathological roles

B Yan, Z Wang - DNA and Cell Biology, 2012 - liebertpub.com
Long noncoding RNAs (lncRNAs) are transcribed RNA molecules> 200 nucleotides in
length. They comprise a diverse class of transcripts that structurally resemble mRNAs, but do …

Short-lived long noncoding RNAs as surrogate indicators for chemical stress in HepG2 cells and their degradation by nuclear RNases

H Tani, A Numajiri, M Aoki, T Umemura, T Nakazato - Scientific Reports, 2019 - nature.com
Long noncoding RNAs (lncRNAs) are non-protein-coding transcripts> 200 nucleotides in
length that have been shown to play important roles in various biological processes. The …

Long non-coding RNA in health and disease

PG Maass, FC Luft, S Bähring - Journal of molecular medicine, 2014 - Springer
Long non-coding RNAs (lncRNAs) interact with the nuclear architecture and are involved in
fundamental biological mechanisms, such as imprinting, histone-code regulation, gene …

Molecular functions and biological roles of long non‐coding RNAs in human physiology and disease

F Kopp - The journal of gene medicine, 2019 - Wiley Online Library
The human genome has been demonstrated to be pervasively transcribed, with a large
fraction of the transcriptome representing non‐protein‐coding RNA species. A relatively …

Long noncoding RNAs: insights from biological features and functions to diseases

X Li, Z Wu, X Fu, W Han - Medicinal research reviews, 2013 - Wiley Online Library
Over the past decade, genome‐wide transcriptomic studies have shown that the mammalian
genome is pervasively transcribed and produces many thousands of transcriptomes without …

Long noncoding RNAs regulate cell growth, proliferation, and apoptosis

J Li, H Tian, J Yang, Z Gong - DNA and cell biology, 2016 - liebertpub.com
The revolutionary findings in nonprotein-coding part of human genome analysis have
revealed a large number of RNA transcripts longer than 200 nucleotides that lack coding …