Inhibition of chitin deacetylases to attenuate plant fungal diseases
L Liu, Y Xia, Y Li, Y Zhou, X Su, X Yan, Y Wang… - Nature …, 2023 - nature.com
Phytopathogenic fungi secrete chitin deacetylase (CDA) to escape the host's immunological
defense during infection. Here, we showed that the deacetylation activity of CDA toward …
defense during infection. Here, we showed that the deacetylation activity of CDA toward …
Deacetylation of chitin oligomers increases virulence in soil-borne fungal pathogens
F Gao, BS Zhang, JH Zhao, JF Huang, PS Jia, S Wang… - Nature Plants, 2019 - nature.com
Soil-borne fungal pathogens that cause crop disease are major threats to agriculture
worldwide. Here, we identified a secretory polysaccharide deacetylase (PDA1) from the soil …
worldwide. Here, we identified a secretory polysaccharide deacetylase (PDA1) from the soil …
Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum,
DE Blair, O Hekmat, AW Schüttelkopf, B Shrestha… - Biochemistry, 2006 - ACS Publications
The fungal pathogen Colletotrichum lindemuthianum secretes an endo-chitin de-N-
acetylase (Cl CDA) to modify exposed hyphal chitin during penetration and infection of …
acetylase (Cl CDA) to modify exposed hyphal chitin during penetration and infection of …
A chitin deacetylase PsCDA2 from Puccinia striiformis f. sp. tritici confers disease pathogenicity by suppressing chitin‐triggered immunity in wheat
M Xiao, D Chen, S Liu, A Chen, A Fang… - Molecular Plant …, 2023 - Wiley Online Library
Plants have the ability to recognize the essential chitin molecule present in the fungal cell
wall, which stimulates the immune response. Phytopathogenic fungi have developed …
wall, which stimulates the immune response. Phytopathogenic fungi have developed …
Expression and specificity of a chitin deacetylase from the nematophagous fungus Pochonia chlamydosporia potentially involved in pathogenicity
A Aranda-Martinez, L Grifoll-Romero, H Aragunde… - Scientific reports, 2018 - nature.com
Chitin deacetylases (CDAs) act on chitin polymers and low molecular weight oligomers
producing chitosans and chitosan oligosaccharides. Structurally-defined, partially …
producing chitosans and chitosan oligosaccharides. Structurally-defined, partially …
What Are the Functions of Chitin Deacetylases in Aspergillus fumigatus?
I Mouyna, S Dellière, A Beauvais, F Gravelat… - Frontiers in Cellular …, 2020 - frontiersin.org
Deacetylation of chitin by chitin deacetylases (Cda) results in the formation of chitosan.
Chitosan, a polymer of β1, 4 linked glucosamine, plays multiple roles in the function of the …
Chitosan, a polymer of β1, 4 linked glucosamine, plays multiple roles in the function of the …
A chitin deacetylase of Podospora anserina has two functional chitin binding domains and a unique mode of action
J Hoßbach, F Bußwinkel, A Kranz, J Wattjes… - Carbohydrate …, 2018 - Elsevier
Chitosan is a structurally diverse biopolymer that is commercially derived from chitin by
chemical processing, but chitin deacetylases (CDAs) potentially offer a sustainable and …
chemical processing, but chitin deacetylases (CDAs) potentially offer a sustainable and …
[HTML][HTML] The chitin deacetylase PoCda7 is involved in the pathogenicity of Pyricularia oryzae
MD Dai, M Wu, Y Li, ZZ Su, FC Lin, XH Liu - Microbiological Research, 2021 - Elsevier
The fungal cell wall plays an essential role in maintaining cellular integrity and facing
complex and changing environmental conditions. Whether a fungus successfully invades a …
complex and changing environmental conditions. Whether a fungus successfully invades a …
A chitin deacetylase from the endophytic fungus Pestalotiopsis sp. efficiently inactivates the elicitor activity of chitin oligomers in rice cells
S Cord-Landwehr, RLJ Melcher, S Kolkenbrock… - Scientific reports, 2016 - nature.com
To successfully survive in plants, endophytes need strategies to avoid being detected by the
plant immune system, as the cell walls of endophytes contain easily detectible chitin. It is …
plant immune system, as the cell walls of endophytes contain easily detectible chitin. It is …
Heterologous expression, characterization and possible functions of the chitin deacetylases, Cda1 and Cda2, from mushroom Coprinopsis cinerea
Y Wang, X Niu, X Guo, H Yu, Z Liu, Z Zhang… - …, 2018 - academic.oup.com
Two chitin deacetylases, Cda1 and Cda2, from Coprinopsis cinerea were expressed and
characterized. Cda1 preferably deacetylates the nonreducing end residue of (GlcNAc) 2, the …
characterized. Cda1 preferably deacetylates the nonreducing end residue of (GlcNAc) 2, the …
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