Several lines of evidence indicate that altered expression of SEPT9 is seen in human
neoplasia. In particular there is evidence of altered expression of the SEPT9_v4 isoform …

Members of the evolutionarily conserved septin family of genes are emerging as key
components of several cellular processes including membrane trafficking, cytokinesis, and …

Septins are an evolutionarily conserved family of GTPases with diverse functions including
roles in cytokinesis that have been implicated in neoplasia. To address the potential role of …

A common feature of the mammalian septin gene family is complex genomic architecture
with multiple alternate splice variants. Septin 9 has 18 distinct transcripts encoding 15 …

Background The evolutionarily conserved septin family of genes encode GTP binding
proteins involved in a variety of cellular functions including cytokinesis, apoptosis …

Altered expression of the human septin gene, SEPT9, and its murine homologue, Sept9, has
been implicated in neoplasia. However, their role (s) in oncogenesis remains poorly …

Abstract Septin9 (Sept9) is a member of the filament-forming septin family of structural
proteins and is associated with a variety of cancers and with hereditary neuralgic …

The septin SEPT11 is a novel member of the highly conserved septin family. Septins are
cytoskeletal GTPases, which form heteropolymeric complexes. They are involved in …

Septins are an evolutionarily conserved family of genes that encode a P loop-based GTP-
binding domain flanked by a polybasic domain and (usually) a coiled-coil region. They have …

Functions of septin cytoskeletal polymers in tumorigenesis are still poorly defined. Their role
in the regulation of cytokinesis and cell migration were proposed to contribute to cancer …