Intrauterine hypoxia (IUH) is a common intrauterine dysplasia that can cause programming
of the offspring cardiovascular system. In this study, we hypothesized that placental …

Background Intrauterine hypoxia (IUH) increases the risk of cardiovascular diseases in
offspring. As a reactive oxygen species (ROS) scavenger, polyamine spermidine (SPD) is …

Prenatal hypoxia is associated with placental oxidative stress, leading to impaired fetal
growth and an increased risk of cardiovascular disease in the adult offspring; however, the …

Myocardial infarction (MI) is associated with a high mortality rate, which is attributed to the
effects of myocyte loss that occurs as a result of ischemia-induced cell death. Very few …

Adverse intrauterine conditions cause fetal growth restriction and increase the risk of adult
cardiovascular disease. We hypothesize that intrauterine hypoxia impairs fetal heart …

Mitochondria-derived oxidative stress during fetal development increases cardiovascular
risk in adult offspring of pregnancies complicated by chronic fetal hypoxia. We investigated …

Offspring born from complicated pregnancies are at greater risk of cardiovascular disease in
adulthood. Prenatal hypoxia is a common pregnancy complication that results in placental …

Intrauterine growth restriction, a common consequence of prenatal hypoxia, is a leading
cause of fetal morbidity and mortality with a significant impact on population health. Hypoxia …

Chronic intrauterine hypoxia is a significant pregnancy complication impacting fetal heart
growth, metabolism, and mitochondrial function, contributing to cardiovascular programming …

Myocardial infarction could result in high morbidity and mortality and heart diseases of
children have becoming prevalent. Functions of spermine administration on cardiomyocytes …