In human vascular anatomy, blood flows from the heart to organs and tissues through a
hierarchical vascular tree, comprising large arteries that branch into arterioles and further …

From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …

A major hurdle in the field of tissue engineering and regenerative medicine remains the
design and construction of larger (> 1 cm3) in vitro tissues for biological studies and …

The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Although the clinical demand for bioengineered blood vessels continues to rise, current
options for vascular conduits remain limited. The synergistic combination of emerging …

Vascular tissue engineering has significant potential to make a major impact on a wide array
of clinical problems. Continued progress in understanding basic vascular biology will be …

Only a few engineered tissues—skin, cartilage, bladder—have achieved clinical success,
and biomaterials designed to replace more complex organs are still far from commercial …

Impaired or damaged blood vessels can occur at all levels in the hierarchy of vascular
systems from large vasculatures such as arteries and veins to meso‐and microvasculatures …

Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …