Engineering of Klebsiella oxytoca for production of 2,3‐butanediol using mixed sugars derived from lignocellulosic hydrolysates

JW Cha, SH Jang, YJ Kim, YK Chang… - GCB Bioenergy, 2020 - Wiley Online Library
Butanediol (2, 3‐BDO) is a promising bulk chemical owing to its high potential in industrial
applications. Here, we engineered Klebsiella oxytoca for the economic production of 2, 3 …

2, 3-Butanediol production using Klebsiella oxytoca ATCC 8724: evaluation of biomass derived sugars and fed-batch fermentation process

YN Guragain, PV Vadlani - Process Biochemistry, 2017 - Elsevier
Abstract For this study, 2, 3-butanediol (BD) fermentation from pure and biomass-derived
sugar were optimized in shake-flask and 5-L bioreactor levels using Klebsiella oxytoca …

Development of an industrial medium for economical 2, 3-butanediol production through co-fermentation of glucose and xylose by Klebsiella oxytoca

XJ Ji, H Huang, J Du, JG Zhu, LJ Ren, S Li… - Bioresource technology, 2009 - Elsevier
An industrial medium containing urea as a sole nitrogen source, low levels of corn steep
liquor and mineral salts as nutrition factors to retain high 2, 3-butanediol production through …

Integrated fermentative production and downstream processing of 2, 3-butanediol from sugarcane bagasse-derived xylose by mutant strain of Enterobacter ludwigii

Y Amraoui, V Narisetty, F Coulon… - ACS Sustainable …, 2021 - ACS Publications
In this study, a mutant strain of Enterobacter ludwigii developed in our previous work, was
evaluated to utilize pure xylose as the sole carbon and energy source for 2, 3-butanediol …

Engineering of Klebsiella oxytoca for the Production of 2,3-Butanediol from High Concentration of Xylose

JW Cha, SH Jang, J Son, J Kim, I Jung… - ACS Sustainable …, 2021 - ACS Publications
Klebsiella oxytoca is widely used for the biological production of 2, 3-butanediol (2, 3-BDO),
a promising platform chemical with a broad range of applications. Here, to improve cell …

Development of a semi‐continuous two‐stage simultaneous saccharification and fermentation process for enhanced 2,3‐butanediol production by Klebsiella oxytoca

SK Moon, DK Kim, JM Park, J Min… - Letters in Applied …, 2018 - academic.oup.com
Klebsiella oxytoca naturally produces a large amount of 2, 3‐butanediol (2, 3‐BD), a
promising chemical with wide industrial applications, along with various by‐products …

Metabolic regulation and optimization of oxygen supply enhance the 2,3‐butanediol yield of the novel Klebsiella sp. isolate FSoil 024

W Chu, K Jiang, P Lu, Y Xu, J Yang, X Wei… - Biotechnology …, 2021 - Wiley Online Library
Abstract Background Biogenic 2, 3‐butanediol (2, 3‐BDO) is a high‐value‐added
compound that can be used as a liquid fuel and a platform chemical. Bioproduction of 2, 3 …

Metabolic engineering of a novel Klebsiella oxytoca strain for enhanced 2, 3-butanediol production

DK Kim, C Rathnasingh, H Song, HJ Lee… - Journal of bioscience …, 2013 - Elsevier
Fermentative 2, 3-butanediol (2, 3-BD) production has been receiving increasing interest for
its potential as a platform chemical intended for the production of synthetic rubbers, plastics …

Engineering of Klebsiella oxytoca for production of 2, 3-butanediol via simultaneous utilization of sugars from a Golenkinia sp. hydrolysate

JH Park, MA Choi, YJ Kim, YC Kim, YK Chang… - Bioresource …, 2017 - Elsevier
The Klebsiella oxytoca was engineered to produce 2, 3-butanediol (2, 3-BDO)
simultaneously utilizing glucose and galactose obtained from a Golenkinia sp. hydrolysate …

Producing 2, 3-butanediol from agricultural waste using an indigenous Klebsiella sp. Zmd30 strain

CL Wong, CC Huang, WB Lu, WM Chen… - Biochemical engineering …, 2012 - Elsevier
This study aimed to develop a low cost and high efficiency process for 2, 3-butanediol (2, 3-
BDO) production by using Klebsiella sp. Zmd30 isolated from a hydrogen-producing …