Advancing cancer biotherapy with proteomics
DF Stroncek, C Burns, BM Martin, L Rossi… - Journal of …, 2005 - journals.lww.com
Proteomics is becoming increasingly important for cancer biotherapy. The development of
high-throughput platforms now allows the analysis of multiple proteins from small quantities …
high-throughput platforms now allows the analysis of multiple proteins from small quantities …
Proteomics and biomarkers in clinical trials for drug development
J Lee, JJ Han, G Altwerger, EC Kohn - Journal of proteomics, 2011 - Elsevier
Proteomics allows characterization of protein structure and function, protein–protein
interactions, and peptide modifications. It has given us insight into the perturbations of …
interactions, and peptide modifications. It has given us insight into the perturbations of …
[HTML][HTML] Proteomics in clinical trials and practice: present uses and future promise
NS Azad, N Rasool, CM Annunziata, L Minasian… - Molecular & Cellular …, 2006 - ASBMB
The study of clinical proteomics is a promising new field that has the potential to have many
applications, including the identification of biomarkers and monitoring of disease, especially …
applications, including the identification of biomarkers and monitoring of disease, especially …
[HTML][HTML] The role of proteomics in the age of immunotherapies
The antigenic landscape of the adaptive immune response is determined by the peptides
presented by immune cells. In recent years, a number of immune-based cancer therapies …
presented by immune cells. In recent years, a number of immune-based cancer therapies …
Proteomics and drug discovery in cancer
Highlights•Proteomics is a valuable tool for biomarker and novel therapeutic target
discovery.•Omics tools are key methodologies designed to target specific biological …
discovery.•Omics tools are key methodologies designed to target specific biological …
Integrative oncoproteomics strategies for anticancer drug discovery
The most significant advantage of proteomic technology is its ability to profile a whole
proteome or subproteome in a single experiment, so that the protein alterations …
proteome or subproteome in a single experiment, so that the protein alterations …
The ongoing evolution of proteomics in malignancy
AS Dhamoon, EC Kohn, NS Azad - Drug Discovery Today, 2007 - Elsevier
The complementary fields of genomics and proteomics offer insights into the molecular
mechanisms of diseases. While genomics seeks to define our genetic substrate, proteomics …
mechanisms of diseases. While genomics seeks to define our genetic substrate, proteomics …
[HTML][HTML] Proteomics to study cancer immunity and improve treatment
G Franciosa, AH Kverneland, AWP Jensen… - Seminars in …, 2023 - Springer
Cancer survival and progression depend on the ability of tumor cells to avoid immune
recognition. Advances in the understanding of cancer immunity and tumor immune escape …
recognition. Advances in the understanding of cancer immunity and tumor immune escape …
Clinical proteomics: revolutionizing disease detection and patient tailoring therapy
E Petricoin, J Wulfkuhle, V Espina… - Journal of proteome …, 2004 - ACS Publications
The evolving discipline of Clinical Proteomics is more than simply describing and
enumerating the systematic changes in the protein constituency of a cell, or just generating …
enumerating the systematic changes in the protein constituency of a cell, or just generating …
[HTML][HTML] Contribution of oncoproteomics to cancer biomarker discovery
WCS Cho - Molecular cancer, 2007 - Springer
Oncoproteomics is the study of proteins and their interactions in a cancer cell by proteomic
technologies. Proteomic research first came to the fore with the introduction of two …
technologies. Proteomic research first came to the fore with the introduction of two …