Advancing cancer biotherapy with proteomics

DF Stroncek, C Burns, BM Martin, L Rossi… - Journal of …, 2005 - journals.lww.com
Proteomics is becoming increasingly important for cancer biotherapy. The development of
high-throughput platforms now allows the analysis of multiple proteins from small quantities …

Proteomics and biomarkers in clinical trials for drug development

J Lee, JJ Han, G Altwerger, EC Kohn - Journal of proteomics, 2011 - Elsevier
Proteomics allows characterization of protein structure and function, protein–protein
interactions, and peptide modifications. It has given us insight into the perturbations of …

[HTML][HTML] Proteomics in clinical trials and practice: present uses and future promise

NS Azad, N Rasool, CM Annunziata, L Minasian… - Molecular & Cellular …, 2006 - ASBMB
The study of clinical proteomics is a promising new field that has the potential to have many
applications, including the identification of biomarkers and monitoring of disease, especially …

[HTML][HTML] The role of proteomics in the age of immunotherapies

SA Hayes, S Clarke, N Pavlakis, VM Howell - Mammalian Genome, 2018 - Springer
The antigenic landscape of the adaptive immune response is determined by the peptides
presented by immune cells. In recent years, a number of immune-based cancer therapies …

Proteomics and drug discovery in cancer

MH Dias, ES Kitano, A Zelanis, LK Iwai - Drug Discovery Today, 2016 - Elsevier
Highlights•Proteomics is a valuable tool for biomarker and novel therapeutic target
discovery.•Omics tools are key methodologies designed to target specific biological …

Integrative oncoproteomics strategies for anticancer drug discovery

R Liu, K Wang, K Yuan, Y Wei… - Expert Review of …, 2010 - Taylor & Francis
The most significant advantage of proteomic technology is its ability to profile a whole
proteome or subproteome in a single experiment, so that the protein alterations …

The ongoing evolution of proteomics in malignancy

AS Dhamoon, EC Kohn, NS Azad - Drug Discovery Today, 2007 - Elsevier
The complementary fields of genomics and proteomics offer insights into the molecular
mechanisms of diseases. While genomics seeks to define our genetic substrate, proteomics …

[HTML][HTML] Proteomics to study cancer immunity and improve treatment

G Franciosa, AH Kverneland, AWP Jensen… - Seminars in …, 2023 - Springer
Cancer survival and progression depend on the ability of tumor cells to avoid immune
recognition. Advances in the understanding of cancer immunity and tumor immune escape …

Clinical proteomics: revolutionizing disease detection and patient tailoring therapy

E Petricoin, J Wulfkuhle, V Espina… - Journal of proteome …, 2004 - ACS Publications
The evolving discipline of Clinical Proteomics is more than simply describing and
enumerating the systematic changes in the protein constituency of a cell, or just generating …

[HTML][HTML] Contribution of oncoproteomics to cancer biomarker discovery

WCS Cho - Molecular cancer, 2007 - Springer
Oncoproteomics is the study of proteins and their interactions in a cancer cell by proteomic
technologies. Proteomic research first came to the fore with the introduction of two …