Abstract A series of novel 1, 2, 3-triazole and chiral Schiff base hybrids 2–6 were
synthesized by Schiff base condensation reaction from pre-prepared parent component of …

In this research, a series of novel hybrid structures of dimethylpyridine-1, 2, 4-triazole Schiff
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …

New pyrazole Schiff bases containing azo groups were synthesized using the condensation
reaction between p-nitrobenzaldehyde and (E)-4-(phenyl)-1-H-pyrazole-3, 5-diamine in the …

In an attempt to design and prepare a new library of anticancer candidates, focused
thiopropargylated benzothiazole was reacted with ethyl azidoacetate and/or ethyl …

Hybrid drugs help combat antibacterial drug resistance, which is an increasing problem
globally. In addition to saving time and money, hybrid drugs offer multiple benefits. Using the …

Abstract Background 1, 2, 4-Triazole derivatives have received much attention due to their
versatile biological properties including antibacterial, antifungal, anticonvulsant …

Schiff base ligands comprising heterocyclic moieties deserve distinct consideration because
of their excellent chemotherapeutic and antioxidant properties as biologically active agents …

Background: 1, 2, 4-triazoles possess a broad spectrum of biological activities such as
analgesic, antimicrobial, antitubercular, anti-inflammatory and antineoplastic activities. This …

Abstract The 1, 3, 4-thiadiazole core has been mainly used as a pharmacological scaffold in
medicinal chemistry. A series of Schiff bases derived from 5-substituted-1, 3, 4-thiadiazole-2 …

In an effort to improve and achieve biologically active anticancer agents, a novel series of 1,
2, 3-triazole-containing hybrids were designed and efficiently synthesized via the Cu …