From vascular corrosion cast to electrical analog model for the study of human liver hemodynamics and perfusion

C Debbaut, D Monbaliu, C Casteleyn… - IEEE Transactions …, 2010 - ieeexplore.ieee.org
Hypothermic machine perfusion (HMP) is experiencing a revival in organ preservation due
to the limitations of static cold storage and the need for better preservation of expanded …

Ex-vivo study of flow dynamics and endothelial cell structure during extended hypothermic machine perfusion preservation of livers

S Jain, H Xu, H Duncan, JW Jones Jr, JX Zhang… - Cryobiology, 2004 - Elsevier
Liver transplantation is often the only effective treatment for end stage liver diseases
resulting from cirrhosis, hepatitis, progressive jaundice, and biliary atresia. Hypothermic …

Modeling the impact of partial hepatectomy on the hepatic hemodynamics using a rat model

C Debbaut, D De Wilde, C Casteleyn… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
Due to the growing shortage of donor livers, more patients are waiting for transplantation.
Living donor liver transplantation may help expanding the donor pool, but is often confronted …

Determination of an adequate perfusion pressure for continuous dual vessel hypothermic machine perfusion of the rat liver

NA 't Hart, A Van Plaats, HGD Leuvenink… - Transplant …, 2007 - Wiley Online Library
Hypothermic machine perfusion (HMP) provides better protection against ischemic damage
of the kidney compared to cold‐storage. The required perfusion pressures needed for …

Pronlonged hypothermic machine perfusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers

H Xu, CY Lee, MG Clemens, JX Zhang - Transplantation, 2004 - journals.lww.com
Background. Although hypothermic machine perfusion (HMP) preservation has been shown
to improve organ function and to expand the organ donor pool, problems still exist with the …

Numerical simulation of the hepatic circulation

A Van Der Plaats, NA 'tHart… - … journal of artificial …, 2004 - journals.sagepub.com
Availability of donor livers and the relatively short preservation time limit the success of liver
transplantation. The use of hypothermic machine perfusion could pave the way for …

Does hypothermic machine perfusion of human donor livers affect risks of sinusoidal endothelial injury and microbial infection? A feasibility study assessing flow …

A Jomaa, K Gurusamy, PN Siriwardana… - Transplantation …, 2013 - Elsevier
BACKGROUND: Hypothermic machine perfusion (HMP) is better than conventional cold
storage in kidney transplantation. Large animal models suggest that HMP may be beneficial …

Hemodynamic, biochemical, and morphological characteristics during preservation of normal porcine livers by hypothermic machine perfusion

D Monbaliu, K Vekemans, R De Vos, J Brassil… - Transplantation …, 2007 - Elsevier
In renal transplantation, hypothermic machine perfusion optimizes preservation of marginal
grafts, assesses their quality prior to transplantation, improves outcome, and may contribute …

[HTML][HTML] Vascular corrosion casting: analyzing wall shear stress in the portal vein and vascular abnormalities in portal hypertensive and cirrhotic rodents

C Van Steenkiste, B Trachet, C Casteleyn… - Laboratory …, 2010 - nature.com
Vascular corrosion casting is an established method of anatomical preparation that has
recently been revived and has proven to be an excellent tool for detailed three-dimensional …

Influence of flow and addition of oxygen during porcine liver hypothermic machine perfusion

K Vekemans, Q Liu, J Brassil, M Komuta… - Transplantation …, 2007 - Elsevier
INTRODUCTION: In contrast with kidneys, data on hypothermic machine perfusion (HMP) of
livers remain scarce. Optimal liver HMP is poorly defined. Superiority of liver HMP over …