Effects of nicorandil on neurobehavioral function, BBB integrity, edema and stereological parameters of the brain in the sub-acute phase of stroke in a rat model

M Owjfard, MR Bigdeli, A Safari, MR Namavar - Journal of biosciences, 2020 - Springer
Blood–brain barrier (BBB) disruption, inflammation, and cell death are the pathogenic
mechanisms of cerebral ischemia/reperfusion (I/R) injury. Nicorandil protects ischemic injury …

Effect of nicorandil on the spatial arrangement of primary motor cortical neurons in the sub-acute phase of stroke in a rat model

M Owjfard, Z Taghadosi, MR Bigdeli, A Safari… - Journal of Chemical …, 2021 - Elsevier
Introduction Ischemic stroke remains a major cause of disability and death worldwide. The
density and the spatial distribution of the primary motor (M1) cortical neurons are important …

Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood–Brain Barrier after Cerebral Ischemia Reperfusion Injury

F He, X Duan, R Dai, Y Li, Q Lin - Journal of Stroke and Cerebrovascular …, 2017 - Elsevier
Damage of the blood–brain barrier (BBB) during the process of cerebral ischemic injury is a
key factor that influences the therapeutic efficacy to the cerebral ischemic injury. This work …

[HTML][HTML] Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury

F He, R Dai, X Zhou, X Li, X Song, H Yan… - Biomedicine & …, 2019 - Elsevier
Objective Cerebral ischemia reperfusion injury (CIRI) is a major cause of ischemic stroke
(IS) deterioration. Considering the intricate mechanism of the pathological process of CIRI …

[PDF][PDF] Sodium butyrate relieves cerebral ischemia-reperfusion injury in mice by inhibiting JNK/STAT pathway.

RX Wang, S Li, X Sui - European Review for Medical & …, 2019 - researchgate.net
OBJECTIVE: The aim of this study was to investigate whether sodium butyrate (NaB)
attenuated cerebral ischemia-reperfusion injury (IRI) in mice by inhibiting JNK/STAT …

S-oxiracetam protect against ischemic stroke via alleviating blood brain barrier dysfunction in rats

L Huang, E Shang, W Fan, X Li, B Li, S He, Y Fu… - European Journal of …, 2017 - Elsevier
The blood brain barrier (BBB) maintains the basic stability of the brain tissue under
physiological conditions, while destroys and exaggerates brain edema and inflammatory …

Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion

JG Wang, SC Bondy, L Zhou, FZ Yang, ZG Ding… - Neurochemical …, 2014 - Springer
Acute inflammation plays an important role in brain damage following cerebral ischemia and
reperfusion (I/R) injury. The present study employed a rat model of middle cerebral artery …

Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down …

M Jiang, J Li, Q Peng, Y Liu, W Liu, C Luo… - Journal of …, 2014 - Springer
Background Mitogen-activated protein kinase (MAPK) signaling pathways are implicated in
inflammatory and apoptotic processes of cerebral ischemia and reperfusion (I/R) injury …

Inhibiting of GRASP65 phosphorylation by DL‐3‐N‐butylphthalide protects against cerebral ischemia‐reperfusion injury via ERK signaling

B Zhu, C Xie, N Hu, X Zhu, C Liu - Behavioural neurology, 2018 - Wiley Online Library
Background and Purpose. The aim of this study was to explore the role of DL‐3‐n‐
butylphthalide (NBP) in cerebral ischemia‐reperfusion injury (CIRI) mice model. The …

The possible damaged mechanism and the preventive effect of monosialotetrahexosylganglioside in a rat model of cerebral ischemia-reperfusion injury

J Zhang, X Fang, Y Zhou, X Deng, Y Lu, J Li, S Li… - Journal of Stroke and …, 2015 - Elsevier
Background The pathogenesis of cerebral ischemia-reperfusion injury (CIRI) is not
completely clear and therapies are limited now. Therefore, our study aimed to investigate the …