Designing a polyvalent vaccine targeting multiple strains of varicella zoster virus using integrated bioinformatics approaches
The Varicella Zoster Virus (VZV) presents a global health challenge due to its dual
manifestations of chickenpox and shingles. Despite vaccination efforts, incomplete …
manifestations of chickenpox and shingles. Despite vaccination efforts, incomplete …
Whole transcriptome analyses reveal differential mRNA and microRNA expression profiles in primary human dermal fibroblasts infected with clinical or vaccine strains …
Licensed live attenuated vaccines have been developed to prevent varicella zoster virus
(VZV) infection, which causes chickenpox and shingles. The genomic sequences of both …
(VZV) infection, which causes chickenpox and shingles. The genomic sequences of both …
Designing a smallpox B-cell and T-cell multi-epitope subunit vaccine using a comprehensive immunoinformatics approach
C Yu, Q Wu, J Xin, Q Yu, Z Ma, M Xue, Q Xu… - Microbiology …, 2024 - Am Soc Microbiol
Smallpox is a highly contagious human disease caused by the variola virus. Although the
disease was eliminated in 1979 due to its highly contagious nature and historical …
disease was eliminated in 1979 due to its highly contagious nature and historical …
Multi-epitope mRNA Vaccine Design that Exploits Variola Virus and Monkeypox Virus Proteins for Elicitation of Long-lasting Humoral and Cellular Protection Against …
D Kovačić, A Salihović - Journal of Medical Science, 2022 - jms.ump.edu.pl
Human monkeypox represents a relatively underexplored infection that has received
increased attention since the reported outbreak in May 2022. Due to its clinical similarities …
increased attention since the reported outbreak in May 2022. Due to its clinical similarities …
A highly conserved epitope-vaccine candidate against varicella-zoster virus induces neutralizing antibodies in mice
R Zhu, J Liu, C Chen, X Ye, L Xu, W Wang, Q Zhao… - Vaccine, 2016 - Elsevier
Varicella-zoster virus (VZV) is a highly infectious agent of varicella and herpes zoster (HZ).
Vaccination is by far the most effective way to prevent these diseases. More safe, stable and …
Vaccination is by far the most effective way to prevent these diseases. More safe, stable and …
Immunoinformatics-aided analysis of RSV fusion and attachment glycoproteins to design a potent multi-epitope vaccine
Respiratory syncytial virus (RSV) usually causes respiratory tract infections of upper airways
in infants and young children. Despite recent medical advances, no approved vaccine is …
in infants and young children. Despite recent medical advances, no approved vaccine is …
Genome-wide reduction in transcriptomal profiles of varicella-zoster virus vaccine strains compared with parental Oka strain using long oligonucleotide microarrays
E Grinfeld, A Ross, T Forster, P Ghazal, PGE Kennedy - Virus Genes, 2009 - Springer
Varicella-Zoster virus (VZV) causes varicella as a primary infection following which it
becomes latent in human ganglia and then reactivates to cause herpes zoster. VZV vaccines …
becomes latent in human ganglia and then reactivates to cause herpes zoster. VZV vaccines …
Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for Escherichia coli-based vaccine design
T Chen, J Sun, S Zhang, T Li, L Liu, W Xue… - Science China Life …, 2023 - Springer
Varicella-zoster virus (VZV) is a highly infectious agent responsible for both varicella and
herpes zoster disease. Despite high efficacy, there remain safety and accessibility concerns …
herpes zoster disease. Despite high efficacy, there remain safety and accessibility concerns …
[HTML][HTML] Formulation of next-generation polyvalent vaccine candidates against three important poxviruses by targeting DNA-dependent RNA polymerase using an …
Background Poxviruses comprise a group of large double-stranded DNA viruses and are
known to cause diseases in humans, livestock animals, and other animal species. The Mpox …
known to cause diseases in humans, livestock animals, and other animal species. The Mpox …
Immunoinformatics and computational approaches driven designing a novel vaccine candidate against Powassan virus
TL Nguyen, H Kim - Scientific Reports, 2024 - nature.com
Powassan virus (POWV) is an arthropod-borne virus (arbovirus) capable of causing severe
illness in humans for severe neurological complications, and its incidence has been on the …
illness in humans for severe neurological complications, and its incidence has been on the …
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