A brief review of the biology of megakaryocytes and platelets and their role in thrombosis associated with particulate air pollution

A Gonzalez-Villalva… - Toxicology and …, 2021 - journals.sagepub.com
Air pollution is a worldwide public health issue and it is associated with millions of premature
deaths due to cancer, thrombosis, and pulmonary and cardiovascular diseases. Thrombosis …

Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation

X Jin, H Yu, B Wang, Z Sun, Z Zhang, QS Liu… - Particle and Fibre …, 2021 - Springer
Background Although airborne fine particulate matter (PM) pollution has been demonstrated
as an independent risk factor for pulmonary and cardiovascular diseases, their currently …

Particulate matter induces prothrombotic microparticle shedding by human mononuclear and endothelial cells

T Neri, L Pergoli, S Petrini, L Gravendonk, C Balia… - Toxicology In Vitro, 2016 - Elsevier
Particulate airborne pollution is associated with increased cardiopulmonary morbidity.
Microparticles are extracellular vesicles shed by cells upon activation or apoptosis involved …

The effect of air pollution on haemostasis

J Emmerechts, MF Hoylaerts - Hämostaseologie, 2012 - thieme-connect.com
Ambient environmental air pollutants include gaseous and particulate components. In
polluted air, especially particulate matter seems responsible for cardiovascular …

Research progress of megakaryocytes and platelets in lung injury

T Hua, G Zhang, Y Yao, H Jia, W Liu - Annals of Medicine, 2024 - Taylor & Francis
The lung is an important site of extramedullary platelet formation, and megakaryocytes in the
lung participate in immune responses in addition to platelet production. In acute lung injury …

Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation

DW Wilson, HH Aung, MW Lame, L Plummer… - Inhalation …, 2010 - Taylor & Francis
Increasingly, evidence suggests a role for a systemic procoagulant state in the pathogenesis
of cardiac dysfunction subsequent to inhalation of airborne particulate matter. The authors …

[HTML][HTML] Megakaryocytes in the lung: History and future perspectives

AC Livada, DN Pariser, CN Morrell - Research and Practice in Thrombosis …, 2023 - Elsevier
A state of the art lecture titled “Megakaryocytes in the Lung” was presented at the London
International Society on Thrombosis and Haemostasis congress in 2022. This lecture …

Extracellular histones mediate the effects of metal-rich air particles on blood coagulation

L Cantone, L Angelici, V Bollati, M Bonzini… - Environmental …, 2014 - Elsevier
Background Epidemiological studies have shown associations of particulate matter (PM)
exposure with hypercoagulability and thrombosis. Extracellular circulating histones have …

Ambient air pollution and thrombosis

S Robertson, MR Miller - Particle and fibre toxicology, 2018 - Springer
Air pollution is a growing public health concern of global significance. Acute and chronic
exposure is known to impair cardiovascular function, exacerbate disease and increase …

Effects of particulate air pollution on hemostasis.

A Nemmar, MF Hoylaerts, B Nemery - Clinics in occupational and …, 2006 - europepmc.org
Exposure to particulate air pollution is associated with acute and chronic cardiovascular
morbidity and mortality. The mechanisms involved in these effects are not fully elucidated …