Despite evidence that the ability to taste is weakened by obesity and can be rescued with
weight loss intervention, few studies have investigated the molecular effects of obesity on …

Background Our sense of taste is critical in defining our food choices and habits. Located
primarily in our tongue, taste buds are small assemblies of constantly renewing sensory …

Background The role of taste perception in the development and persistence of obesity is
currently unclear due to conflicting results from psychophysical and other studies. No study …

The incidence of obesity has dramatically increased in recent years, and poses a public
health challenge for which an effective and scalable intervention strategy is yet to be found …

Introduction Obesity is a growing epidemic that causes many serious health related
complications. While the causes of obesity are complex, there is conclusive evidence that …

Background The mammalian taste bud, a complex collection of taste sensory cells,
supporting cells, and immature basal cells, is the structural unit for detecting taste stimuli in …

Sweet perception promotes food intake, whereas that of bitterness is inhibitory. Surprisingly,
the expression of sweet G protein-coupled taste receptor (GPCTR) subunits (T1R2 and …

The mammalian taste bud is an onion-shaped epithelial structure with 50–100 tightly packed
cells, including taste receptor cells, supporting cells, and basal cells. Taste receptor cells …

Although inflammatory responses are a critical component in defense against pathogens,
too much inflammation is harmful. Mechanisms have evolved to regulate inflammation …

Palatable foods lead to overeating, and it is almost a forgone conclusion that it is also an
important contributor to the current obesity epidemic–there is even talk about food addiction …