Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Strategies of engineering nanoparticles for treating neurodegenerative disorders

K Tu Nguyen, M Nguyet Pham, T Van Vo… - Current Drug …, 2017 - ingentaconnect.com
Background: Neurodegenerative disorders (NDs) are typically referred to Alzheimer's
disease, Parkinson's diseases, amyotrophic lateral sclerosis and prion disease. These are …

Neurotherapeutic applications of nanoparticles in Alzheimer's disease

JK Sahni, S Doggui, J Ali, S Baboota, L Dao… - Journal of Controlled …, 2011 - Elsevier
A rapid increase in incidence of neurodegenerative disorders has been observed with the
aging of the population. Alzheimer's disease (AD) is the most common neurodegenerative …

Recent advances in biomimetic nanodelivery systems: new brain-targeting strategies

J Liao, L Fan, Y Li, QQ Xu, LY Xiong, SS Zhang… - Journal of Controlled …, 2023 - Elsevier
In recent years, brain diseases have seriously threatened human health due to their high
morbidity and mortality. Achieving efficient drug delivery to provide satisfactory therapeutic …

Drug delivery to the brain across the blood–brain barrier using nanomaterials

YH Tsou, XQ Zhang, H Zhu, S Syed, X Xu - Small, 2017 - Wiley Online Library
A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …

Nanoscience in targeted brain drug delivery

M Çetin, E Aytekin, B Yavuz… - … methods for neurological …, 2017 - Elsevier
Neurological diseases are one of the most serious life-threatening diseases worldwide. The
currently applied strategies for the treatment of neurological diseases are not able to provide …

Targeted delivery of nano-therapeutics for major disorders of the central nervous system

H Gao, Z Pang, X Jiang - Pharmaceutical research, 2013 - Springer
Major central nervous system (CNS) disorders, including brain tumors, Alzheimer's disease,
Parkinson's disease, and stroke, are significant threats to human health. Although …

Alzheimer's disease targeted nano-based drug delivery systems

G Altinoglu, T Adali - Current Drug Targets, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disease, and is part of a
massive and growing health care burden that is destroying the cognitive function of more …

[HTML][HTML] Nanoparticle-mediated brain drug delivery: overcoming blood–brain barrier to treat neurodegenerative diseases

C Saraiva, C Praça, R Ferreira, T Santos… - Journal of controlled …, 2016 - Elsevier
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …