Introduction Metformin toxicity following therapeutic use or overdose may result in metabolic
acidosis with hyperlactatemia. This study aims to assess the relationship between serum …

Objective: Metformin-associated lactic acidosis (MALA) is a complication of metformin
overdose. Recommendations for observation time after an acute ingestion to monitor for …

Introduction The prevalence of type 2 diabetes (T2D) continues to rise across the world.
Metformin is still considered the “gold standard” and is, therefore, increasingly prescribed …

Background Although metformin‐associated lactic acidosis is well described, there is less
information on metformin overdose and whether it is of similar severity. Aims This study aims …

INTRODUCTION: Metformin-associated lactic acidosis (MALA) is well described in patients
taking therapeutic metformin who develop renal failure or other serious comorbid conditions …

BACKGROUND The major risk associated with metformin is lactic acidosis. The incidence of
lactic acidosis is not clear. Hypoglycemia is not expected to be a major concern after …

Introduction Metformin-associated lactic acidosis is a well-described and commonly
encountered condition associated with significant morbidity and mortality. Patients with …

Purpose To assess whether extracorporeal treatment (ECTR) improves outcome of patients
with metformin-associated lactic acidosis (MALA) and to evaluate the clinical applicability of …

Objective: The aim of this study was to evaluate the frequency of metformin-associated lactic
acidosis in our metformin-intoxicated patients, the general approach for their management …

Introduction Metformin poisoning with lactic acidosis is an uncommon yet clinically serious
condition related to the inhibition of normal aerobic metabolism. Toxicity may occur after an …