Effect of metformin on testosterone levels in male patients with type 2 diabetes mellitus treated with insulin

T Cai, Y Hu, B Ding, R Yan, B Liu, L Cai… - Frontiers in …, 2021 - frontiersin.org
Aim To explore the chronic effects of metformin on testosterone levels in men with type 2
diabetes mellitus (T2DM). Methods This is a secondary analysis of a real-world study …

Rapid changes in serum testosterone in men with newly diagnosed type 2 diabetes with intensive insulin and metformin

Y Hu, B Ding, Y Shen, RN Yan, FF Li, R Sun… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE To investigate the effect of metformin on testosterone levels in men with type 2
diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS Seventy men with newly …

[HTML][HTML] Association between testosterone with type 2 diabetes in adult males, a meta-analysis and trial sequential analysis

J Zhang, X Li, Z Cai, H Li, B Yang - The Aging Male, 2020 - Taylor & Francis
Objective We performed this meta-analysis to assess serum testosterone changes in adult
males with Type 2 diabetes (T2DM). Methods PubMed, Embase, Web of Science, and …

[HTML][HTML] Comparison of testosterone levels in patients with and without type 2 diabetes

N Kumari, A Khan, U Shaikh, K Lobes, D Kumar… - Cureus, 2021 - ncbi.nlm.nih.gov
Results The mean total testosterone level was significantly lower in diabetic patients
compared to the non-diabetic patients (8.9±5.1 mmol/L vs. 14.1±7.2 mmol/L; p-value:< …

Short‐term combined treatment with exenatide and metformin is superior to glimepiride combined metformin in improvement of serum testosterone levels in type 2 …

N Shao, XY Yu, YM Yu, BW Li, J Pan, WH Wu… - Andrologia, 2018 - Wiley Online Library
Men with type 2 diabetes (T2D) and obesity are often characterised by low testosterone (T).
We aimed to determine whether exenatide (EXE) combined metformin (MET) treatment has …

Effect of testosterone on insulin sensitivity, oxidative metabolism and body composition in aging men with type 2 diabetes on metformin monotherapy

LV Magnussen, D Glintborg, P Hermann… - Diabetes, Obesity …, 2016 - Wiley Online Library
Aims To evaluate the effect of testosterone replacement therapy (TRT) on body composition,
insulin sensitivity, oxidative metabolism and glycaemic control in aging men with lowered …

Testosterone level in men with type 2 diabetes mellitus and related metabolic effects: A review of current evidence

KKT Cheung, AOY Luk, WY So… - Journal of diabetes …, 2015 - Wiley Online Library
A significant proportion of patients with type 2 diabetes mellitus have a low testosterone
level relative to reference ranges based on healthy young men. Only a small number of …

Effect of testosterone treatment on glucose metabolism in men with type 2 diabetes: a randomized controlled trial

EJ Gianatti, P Dupuis, R Hoermann, BJ Strauss… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE To determine whether testosterone therapy improves glucose metabolism in
men with type 2 diabetes (T2D) and lowered testosterone. RESEARCH DESIGN AND …

Testosterone level and risk of type 2 diabetes in men: a systematic review and meta-analysis

Q Yao, B Wang, X An, J Zhang… - Endocrine …, 2018 - ec.bioscientifica.com
Background Type 2 diabetes is a risk factor for testosterone deficiency and impaired sex
steroid status. Some studies also investigated the association of testosterone level with …

Type 2 diabetes mellitus and testosterone: A meta‐analysis study

G Corona, M Monami, G Rastrelli… - … journal of andrology, 2011 - Wiley Online Library
Several studies suggest that type 2 diabetes mellitus (T2DM) is often associated with male
hypogonadism. Despite the well‐known link, the role of testosterone replacement therapy …