Macrophages are types of immune cells, with ambivalent functions in tumor growth, which
depend on the specific environment in which they reside. Tumor-associated macrophages …

Macrophages are phagocytes that serve as a first line of defense against pathogenic insults
to tissues. These innate immune cells mount proinflammatory responses to pathogens and …

Simple Summary Tumor-associated macrophages (TAMs) are the most prevalent
immunosuppressive myeloid cells in the tumor microenvironment, playing significant …

Established evidence demonstrates that tumor-infiltrating myeloid cells promote rather than
stop-cancer progression. Tumor-associated macrophages (TAMs) are abundantly present at …

Macrophages are a major component of the tumor microenvironment and orchestrate
various aspects of immunity. Within tumors, macrophages can reversibly alter their endotype …

In the last decade, it has been well-established that tumor-infiltrating myeloid cells fuel not
only the process of carcinogenesis through cancer-related inflammation mechanisms, but …

Tumor-associated macrophages (TAMs) are a major cellular component of numerous tumor
types. TAM-targeted therapies include depletion strategies, inhibiting their effector functions …

Macrophages are innate immune cells that are ubiquitously distributed throughout the
vertebrate body. Macrophages orchestrate sophisticated processes in development …

Macrophages sustain tumour progression by facilitating angiogenesis, promoting
immunosuppression, and enhancing cancer cell invasion and metastasis. They also …

Tumor-associated macrophages (TAMs) exert integrated effects in all aspects of tumor
progression, including tumor cell proliferation, angiogenesis, invasion, and metastasis …