Flavonoids from Whole-Grain Oat Alleviated High-Fat Diet-Induced Hyperlipidemia via Regulating Bile Acid Metabolism and Gut Microbiota in Mice

R Duan, X Guan, K Huang, Y Zhang, S Li… - Journal of Agricultural …, 2021 - ACS Publications
A high-fat diet (HFD) causes hyperlipidemia, which worsens disturbances in bile acid (BA)
metabolism and gut microbiota. This study aimed to investigate the regulation of flavonoids …

Whole grain benefit: Synergistic effect of oat phenolic compounds and β-glucan on hyperlipidemia via gut microbiota in high-fat-diet mice

Y Li, C Qin, L Dong, X Zhang, Z Wu, L Liu, J Yang… - Food & Function, 2022 - pubs.rsc.org
Increasing evidence has confirmed that whole grain oats are effective in regulating
hyperlipidemia. However, which specific ingredient is crucial remains unclear. This study …

Oat phenolic compounds regulate metabolic syndrome in high fat diet-fed mice via gut microbiota

L Dong, C Qin, Y Li, Z Wu, L Liu - Food Bioscience, 2022 - Elsevier
This study aimed to better understand the beneficial effect of oat phenolic compounds (OPC)
in improving metabolic syndrome via regulating metabolites and gut microbiota composition …

Apple polyphenol extract improves high-fat diet-induced hepatic steatosis by regulating bile acid synthesis and gut microbiota in C57BL/6 male mice

D Li, Y Cui, X Wang, F Liu, X Li - Journal of agricultural and food …, 2021 - ACS Publications
Our previous study showed that apple polyphenol extract (APE) ameliorated high-fat diet-
induced hepatic steatosis in C57BL/6 mice by targeting the LKB1/AMPK pathway; to …

Effects of oats, tartary buckwheat, and foxtail millet supplementation on lipid metabolism, oxido-inflammatory responses, gut microbiota, and colonic SCFA composition …

Y Wang, W Qi, X Guo, G Song, S Pang, W Fang… - Nutrients, 2022 - mdpi.com
Coarse cereals rich in polyphenols, dietary fiber, and other functional components exert
multiple health benefits. We investigated the effects of cooked oats, tartary buckwheat, and …

Probiotic-fermented rice buckwheat alleviates high-fat diet-induced hyperlipidemia in mice by suppressing lipid accumulation and modulating gut microbiota

J Yan, Q Xue, W Chen, K Wang, D Peng, J Jiang… - Food Research …, 2022 - Elsevier
Hyperlipidemia is associated with lipid metabolic disorders, chronic inflammation, and
intestinal dysbiosis. Previous studies have shown that the metabolic improvement of high-fat …

Nuciferine Protects Against High-Fat Diet-Induced Hepatic Steatosis via Modulation of Gut Microbiota and Bile Acid Metabolism in Rats

J Sun, J Fan, T Li, X Yan, Y Jiang - Journal of Agricultural and …, 2022 - ACS Publications
Our previous study showed that nuciferine (NF) attenuated non-alcoholic fatty liver disease
(NAFLD), which is attributed to a high-fat diet (HFD) through reinforcing intestinal barrier …

Oryzanol attenuates high fat and cholesterol diet-induced hyperlipidemia by regulating the gut microbiome and amino acid metabolism

S Yan, J Chen, L Zhu, T Guo, D Qin, Z Hu… - Journal of Agricultural …, 2022 - ACS Publications
Hyperlipidemia is intricately associated with the dysregulation of gut microbiota and host
metabolomes. This study explored the antihyperlipidemic function of oryzanol and …

Modulation of gut microbiota by fucoxanthin during alleviation of obesity in high-fat diet-fed mice

X Sun, H Zhao, Z Liu, X Sun, D Zhang… - Journal of agricultural …, 2020 - ACS Publications
Fucoxanthin (Fx), an allenic carotenoid from brown seaweeds or diatoms, has been
demonstrated to prevent obesity. Gut dysbiosis and inflammation are two counted important …

Novel sesquiterpene glycoside from loquat leaf alleviates type 2 diabetes mellitus combined with nonalcoholic fatty liver disease by improving insulin resistance …

J Chen, X Ding, R Wu, B Tong, L Zhao… - Journal of agricultural …, 2021 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD) is strongly associated with type 2 diabetes mellitus
(T2DM). Sesquiterpene glycosides from loquat leaf achieved beneficial effects on metabolic …