The role of the tumour microenvironment in the angiogenesis of pituitary tumours

P Marques, S Barry, E Carlsen, D Collier, A Ronaldson… - Endocrine, 2020 - Springer
Purpose Angiogenesis has been studied in pituitary neuroendocrine tumours (PitNETs), but
the role of the tumour microenvironment (TME) in regulating PitNET angiogenesis remains …

Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours

P Marques, S Barry, E Carlsen, D Collier… - Acta neuropathologica …, 2019 - Springer
Non-tumoural cells within the tumour microenvironment (TME) influence tumour
proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary …

Analysis of tumor angiogenesis and immune microenvironment in non-functional pituitary endocrine tumors

M Sato, R Tamura, H Tamura, T Mase, K Kosugi… - Journal of clinical …, 2019 - mdpi.com
Cavernous sinus (CS) invasion is an aggressive behavior exhibited by pituitary
neuroendocrine tumors (PitNETs). The cause of CS invasion in PitNETs has not been fully …

Immune landscape of pituitary tumors reveals association between macrophages and gonadotroph tumor invasion

M Principe, M Chanal, MD Ilie, A Ziverec… - The Journal of …, 2020 - academic.oup.com
Abstract Purpose Pituitary neuroendocrine tumors (PitNETs) are frequent intracranial
neoplasms that present heterogenic characteristics. Little is known about the immune cell …

The expression of neural cell adhesion molecule and the microenvironment of pituitary neuroendocrine tumours

P Marques, S Barry, E Carlsen, D Collier… - Journal of …, 2021 - Wiley Online Library
The neural cell adhesion molecule (NCAM) has previously been studied in pituitary
neuroendocrine tumours (PitNETs), but its role in tumour biology and aggressiveness …

The microenvironment of pituitary tumors—biological and therapeutic implications

MD Ilie, A Vasiljevic, G Raverot, P Bertolino - Cancers, 2019 - mdpi.com
The tumor microenvironment (TME) includes resident and infiltrative non-tumor cells, as well
as blood and lymph vessels, extracellular matrix molecules, and numerous soluble factors …

The tumour microenvironment of pituitary neuroendocrine tumours

P Marques, AB Grossman, M Korbonits - Frontiers in Neuroendocrinology, 2020 - Elsevier
The tumour microenvironment (TME) includes a variety of non-neoplastic cells and non-
cellular elements such as cytokines, growth factors and enzymes surrounding tumour cells …

Role of tumor microenvironment in pituitary neuroendocrine tumors: New approaches in classification, diagnosis and therapy

DA Tapoi, ML Popa, C Tanase, D Derewicz… - Cancers, 2023 - mdpi.com
Simple Summary Pituitary adenomas are highly prevalent intracranial neoplasms that can
be locally invasive in up to half of cases. Consequently, using the term “PitNETs”(pituitary …

Angiogenesis in pituitary adenomas

S Yamada, K Takada - Microscopy research and technique, 2003 - Wiley Online Library
Angiogenesis, which is the formation of new blood vessels from preexisting capillaries, plays
an important role in tumor growth and metastasis. In this review, the focus is on …

HGF/c-met system targeting PI3K/AKT and STAT3/phosphorylated-STAT3 pathways in pituitary adenomas: an immunohistochemical characterization in view of …

M Trovato, ML Torre, M Ragonese, A Simone, R Scarfì… - Endocrine, 2013 - Springer
The ligand/receptor hepatocyte growth factor (HGF)/c-met signaling system promotes
cellular growth and angiogenesis through PI3K/phosphor-Akt and STAT3/phosphor-STAT3 …