The extensive pulmonary alveolar and capillary networks make the lungs highly susceptible
to cell and tissue injury from pathogens or toxic environmental agents present either in the …

Surfactant therapy for acute lung injury/acute respiratory d... : Current Opinion in Critical
Care Surfactant therapy for acute lung injury/acute respiratory distress syndrome : Current …

Objectives To outline both the preclinical and clinical data demonstrating surfactant
alterations in acute lung injury, which provide the rationale for testing exogenous surfactant …

The importance of pulmonary surfactant in maintaining normal lung function, and the
observations that alterations in endogenous surfactant contribute to the lung dysfunction …

Acute lung injury and acute respiratory distress syndrome (ARDS) are characterised by
severe hypoxemic respiratory failure and poor lung compliance. Despite advances in clinical …

▪ Abstract A number of conditions, such as pneumonia, trauma, or systemic sepsis arising
from the gut, may result in the acute respiratory distress syndrome (ARDS). Because of its …

OBJECTIVE: To evaluate whether exogenous surfactant therapy may be useful in adult
patients with acute lung injury or acute respiratory distress syndrome, using a meta-analysis …

Rationale: Compositional changes in surfactant and/or decreased surfactant content of the
lungs are common features in patients with acute respiratory failure. Instillation of …

We evaluated the effects of various ventilation strategies on the efficacy of exogenous
surfactant therapy in lung-injured adult rabbits. Lung injury was induced by repetitive whole …

The acute respiratory distress syndrome (ARDS) is a frequent, life-threatening disease in
which a marked increase in alveolar surface tension has been repeatedly observed. It is …