[HTML][HTML] Human chorionic villous differentiation and placental development

J Kojima, M Ono, N Kuji, H Nishi - International Journal of Molecular …, 2022 - mdpi.com
In humans, the placenta provides the only fetomaternal connection and is essential for
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …

[PDF][PDF] Developmental cell biology of human villous trophoblast: current research problems

JD Aplin - Int J Dev Biol, 2010 - academia.edu
The common gestational pathologies are placental and developmental in origin. However,
much remains to be learned about the key events of morphogenesis and growth in the …

Early development of the human placenta and pregnancy complications

K Haram, JH Mortensen, O Myking… - The Journal of …, 2020 - Taylor & Francis
An adequately sized placenta at a suitable site with appropriate depth and centripetal
progression of implantation are the major factors for optimal fetal development. The …

An integrative view on the physiology of human early placental villi

B Huppertz, D Ghosh, J Sengupta - Progress in Biophysics and Molecular …, 2014 - Elsevier
The placenta is an indispensable organ for intrauterine protection, development and growth
of the embryo and fetus. It provides tight contact between mother and conceptus, enabling …

Transcriptomic signatures of villous cytotrophoblast and syncytiotrophoblast in term human placenta

C Rouault, K Clément, M Guesnon, C Henegar… - Placenta, 2016 - Elsevier
During pregnancy, the placenta ensures multiple functions, which are directly involved in the
initiation, fetal growth and outcome of gestation. The placental tissue involved in maternal …

[HTML][HTML] Human placenta and trophoblast development: key molecular mechanisms and model systems

M Knöfler, S Haider, L Saleh, J Pollheimer… - Cellular and Molecular …, 2019 - Springer
Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

Human embryonic stem cells as a model for trophoblast differentiation

TG Golos, LM Pollastrini… - … in reproductive medicine, 2006 - thieme-connect.com
The earliest stages of human development profoundly influence the success of pregnancy
and maternal as well as fetal health. One of the most critical developmental processes is the …

Establishment of Trophoblast‐Like Tissue Model from Human Pluripotent Stem Cells in Three‐Dimensional Culture System

K Cui, Y Zhu, Y Shi, T Chen, H Wang, Y Guo… - Advanced …, 2022 - Wiley Online Library
The placenta has a lifelong impact on the health of both the mother and fetus. Despite its
significance, human early placental development is poorly understood due to the limited …

Unique features and emerging in vitro models of human placental development

S Shibata, EH Kobayashi, N Kobayashi… - Reproductive …, 2020 - Wiley Online Library
Background The placenta is an essential organ for the normal development of mammalian
fetuses. Most of our knowledge on the molecular mechanisms of placental development has …

[HTML][HTML] Embryology, placenta

EJ Herrick, B Bordoni - 2019 - europepmc.org
The placenta is a vital organ with multiple functions, such as endocrine, immune, and
physiological. The placenta is formed gradually during the first three months of pregnancy …