Amyloid proteins were recognized as the crucial cause of many senile diseases. In this
study, the inhibitory effects of Sennoside A (SA) and Sennoside C (SC) on amyloid …

Silybin is a flavonoid lignin compound consisting of two diastereomers with nearly equal
molar ratios. It has been reported that silybin can effectively inhibit the aggregation of …

Amyloid depositions of proteins play crucial roles in a wide variety of degenerative disorders
called amyloidosis. In the present study, we used hen egg white lysozyme (HEWL), as an in …

Misfolding proteins could form oligomers or amyloid fibers, which can cause a variety of
amyloid-associated diseases. Thus, the inhibition of protein misfolding and fibrillation is a …

Amyloid fibrillation is closely associated with a series of neurodegenerative diseases.
According to that, the intermediate soluble oligomers and protofibrils are more toxic; …

The misfolding of soluble protein to amyloid fibers or oligomers leads to cell membrane
rupture, cell death, and a variety of amyloid-related diseases. Hence, inhibition of protein …

Methods: Acidic pH and high temperatures were used to drive the protein towards amyloid
formation. Lysozyme was dissolved at 2 mg/mL in 50mM glycine buffer (pH 2.5), and then …

P-Coumaric acid (p-CA) is a plant metabolite with anti-inflammatory and antioxidant effects.
Due to its therapeutic potential, p-CA has attracted much attention from the scientific …

Abstract Chalcones (α-phenyl-β-benzoylethylene) and their natural-source derivatives have
been investigated for their remarkable biological activities, like neuroprotective, anti …

Amyloid fibrillogenesis of proteins is known to be the root cause of a large number of
diseases like Parkinson's, Alzheimer's, and Huntington's disease, spongiform …