Gap junction channels provide an enclosed conduit for direct exchanges of signalling
molecules, including ions and small metabolites between cells. This system of …

Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular
hypertension. Background Connexin 40 (Cx40) is a gap junction protein expressed in …

Cellular interaction in blood vessels is maintained by multiple communication pathways,
including gap junctions. They consist of intercellular channels ensuring direct interaction …

Renin secretion and synthesis in renal juxtaglomerular cells are controlled by short feed
back loops involving angiotensin II and the intrarenal blood pressure. The operating …

Connexin (Cx) proteins are known to play a role in cell-to-cell communication via
intercellular gap junction channels or transiently open hemichannels. Previous studies have …

To investigate the function of Cx43 during hypertension, we studied the mouse line
Cx43KI32 (KI32), in which the coding region of Cx32 replaces that of Cx43. Within the …

Cellular interaction in vessels is achieved by multiple communication pathways, including
gap junctions (GJs). They provide intercellular channels, allowing direct interaction of …

Gap junctions are formed in the cardiovascular system by connexin40 (Cx40), Cx37, Cx43,
and Cx45. These low resistance channels allow the transfer of ions and small molecules …

Renin secretion is regulated by coordinated signaling between the various cells of the
juxtaglomerular apparatus. The renin-secreting cells (RSC), which play a major role in the …

Connexins form intercellular channels that span two plasma membranes and directly couple
the cytoplasm of adjacent cells. This morphological contact enables the exchange of ions …