Characterisation, utilisation and clinical relevance of isolated perfused heart models of ischaemia-induced ventricular fibrillation
MJ Curtis - Cardiovascular Research, 1998 - academic.oup.com
The isolated perfused heart has been used increasingly during the last decade as a model
for identifying actions of drugs on ventricular fibrillation (VF) induced by myocardial …
for identifying actions of drugs on ventricular fibrillation (VF) induced by myocardial …
Rat models of ventricular fibrillation following acute myocardial infarction
LA Hundahl, J Tfelt-Hansen… - Journal of …, 2017 - journals.sagepub.com
A number of animal models have been designed in order to unravel the underlying
mechanisms of acute ischemia-induced arrhythmias and to test compounds and …
mechanisms of acute ischemia-induced arrhythmias and to test compounds and …
Development and characterization of a mouse in vitro model of ischaemia-induced ventricular fibrillation
CL Stables, MJ Curtis - Cardiovascular research, 2009 - academic.oup.com
Aims We sought to generate a mouse Langendorff model of ischaemia-induced ventricular
fibrillation (VF) that does not depend on triggers such as programmed electrical stimulation …
fibrillation (VF) that does not depend on triggers such as programmed electrical stimulation …
Evolution of activation patterns during long-duration ventricular fibrillation in dogs
Although resuscitation for sudden cardiac arrest attempts are frequently not instituted for
several minutes after the onset of ventricular fibrillation (VF), previous mapping studies have …
several minutes after the onset of ventricular fibrillation (VF), previous mapping studies have …
Phase 2 ventricular arrhythmias in acute myocardial infarction: a neglected target for therapeutic antiarrhythmic drug development and for safety pharmacology …
H Clements‐Jewery, DJ Hearse… - British journal of …, 2005 - Wiley Online Library
Ventricular fibrillation (VF), a cause of sudden cardiac death (SCD) in the setting of acute
myocardial infarction (MI), remains a major therapeutic challenge. In humans, VF may occur …
myocardial infarction (MI), remains a major therapeutic challenge. In humans, VF may occur …
Ventricular fibrillation threshold and vulnerable period in the isolated perfused rat heart
WF Lubbe, OL Bricknell… - Cardiovascular Research, 1975 - academic.oup.com
AUTHORS'SYNOPSIS Ventricular fibrillation threshold (VFT) measurements were obtained
in the isolated perfused rat heart. Detailed morphology of the vulnerable period (VP) could …
in the isolated perfused rat heart. Detailed morphology of the vulnerable period (VP) could …
Experimental models of ventricular tachycardia and fibrillation caused by ischemia and infarction.
AL Wit, MJ Janse - Circulation, 1992 - europepmc.org
Experimental animal models of ventricular arrhythmias have been developed to elucidate
mechanisms of arrhythmogenesis in humans. Studies of animal models have enabled the …
mechanisms of arrhythmogenesis in humans. Studies of animal models have enabled the …
A comprehensive review and analysis of 25 years of data from an in vivo canine model of sudden cardiac death: implications for future anti-arrhythmic drug …
GE Billman - Pharmacology & therapeutics, 2006 - Elsevier
Sudden cardiac death resulting from ventricular tachyarrhythmias remains the leading cause
of death in industrially developed countries, accounting for between 300,000 and 500,000 …
of death in industrially developed countries, accounting for between 300,000 and 500,000 …
Electrical activation during ventricular fibrillation in the subacute and chronic phases of healing canine myocardial infarction
RS Damle, NS Robinson, DZ Ye, SI Roth, R Greene… - Circulation, 1995 - Am Heart Assoc
Background Little information is available regarding the effects of myocardial infarction on
the characteristics of ventricular fibrillation (VF). Epicardial activation during VF can be …
the characteristics of ventricular fibrillation (VF). Epicardial activation during VF can be …
Quantification of effects of global ischemia on dynamics of ventricular fibrillation in isolated rabbit heart
R Mandapati, Y Asano, WT Baxter, R Gray… - Circulation, 1998 - Am Heart Assoc
Background—Ventricular fibrillation (VF) leads to global ischemia of the heart. After 1 to 2
minutes of onset, the VF rate decreases and appears more organized. The objectives of this …
minutes of onset, the VF rate decreases and appears more organized. The objectives of this …
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