Traditional vaccines, based on the administration of killed or attenuated microorganisms,
have proven to be among the most effective methods for disease prevention. Safety issues …

A major challenge for current vaccine development is the fact that many new subunit
vaccines based on highly purified recombinant proteins are poorly immunogenic and …

Highlights•Successful immunotherapies must target a precise phenotype and strength of an
immune response.•Supramolecular materials may offer strategies for identifying and eliciting …

Vaccines represent the most efficient tool for preventing diseases caused by infectious
pathogens. During the last century significant progress has been made in vaccine …

Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

Vaccination remains a key tool in the protection and eradication of diseases. However, the
development of new safe and effective vaccines is not easy. Various live organism based …

Introduction: Adjuvants form an integral component in most of the inactivated and subunit
vaccine formulations. Careful and proper selection of adjuvants helps in promoting …

Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …

Vaccines are the most effective and cost-efficient method for preventing diseases caused by
infectious pathogens. Despite the great success of vaccines, development of safe and strong …

Developing efficient and safe adjuvants for use in human vaccines remains both a challenge
and a necessity. Past approaches have been largely empirical and generally used a single …